Crocus sativus, L.

Natural order , Iridaceæ.

Common names , Saffron, Safran.

Preparation , Trituration of the dried stigmas.

Authorities.

1 , Stapf, Beitrage zur rein. Arzm., proving with "a small quantity of the tincutre shaken up in water; none of the provers took over 12 grains of saffron, several far less;" 2 , Gross, ibid.; 3 , Thorer, ibid.; 4 , Wahle, ibid.; 5 , Boerhaave, in Chem. ex. Msct. Lugd. Batav. Process, 59, from Stapf; 6 , Carp. Pezold, Obs., 55, Vratislav., 1715, effects of a drachm of saffron on a girl of 18, from Stapf; 7 , Riverius, Opp. Med., p. 136, from Stapf; 8 , Tralles, de Opio, Sect. 1, p. 114, effects of the odor, from putting Saffron up in papers in a heated room (from original); 9 , Schulz, Prælut. in Disp. Brandenb., 236, from Stapf; 10 , Zacut. Lusit. ap. Fricc. de Ven., p. 394, from Stapf; 11 , Bergius, Mat. Med., 1, p. 38, from Roth's résumé; 12 , Sundelin, effects of freshly blooming Crocus, from A. H. Z., 20, 288; 13 , same, a girl took 6 grains in one afternoon.

MIND

Emotional.
Childish foolishness; silly dementia, 5.
Suddenly there arises before her fancy a concert which she attended a long time since, as vividly as if she were listening to it; she even imagines she can hear the different instruments; after a time this vivid recollection of the past disappears, and she is no more able to recall the music, 1.
An unpleasant sensation, as if he were longing for something without knowing what, with a kind of apprehension, where with, however, he was very joyous, 1.
Inclination to sing (after half an hour), 1.
If any one happens to sing a single musical note, she begins involuntarily to sing, and then is obliged to laugh at herself; she, however, soon sings again in spite of her determination to stop, 1.
Even when out of humor, quiet repetition of a lively melody, 1.
Stinging in sleep, 1.
Children begin to laugh immediately on smelling the bottle, 9.
Almost constant unbecoming laughter, 5. [10.]
Immoderate laughter, as if he would die, 1.
Sardonic laughter, and attacks of morbid jollity, 13.
It causes a lively mood in a most unnatural degree, 13.
Lively and joyous mood, much more than natural, 1.
Very lively mood, witty, jocose, excessively talkative, 1.
Very gay and laughing mood in a dream, 1.
Great joyousness even in those who are naturally melancholic and hypochondriac, 1.
Excessive gayety, bordering upon delirium; paleness, headache, obscuration of vision, 10.
Irresistible inclination to joke and laugh, with great prostration, and great dilatation of the pupils (after four hours and a half), 1.
Melancholic, sad hypochondriac mood, 1. [20.]
Deep melancholy, 11.
During an interesting lecture he became suddenly and peculiarly sad, so that he was unable in spite of every exertion to fix his mind upon the subject (after ten hours), 1.

HEAD

Confusion and Vertigo.
Confusion in the head; momentary vertigo, with dull pain in the eyes, 1.
Tensive confusion first in the forehead, soon afterwards in the whole head, as if intoxicated (after ten minutes), 1.
Vertigo and much confusion of the head, 1.
Dizziness and staggering after rising from lying down, in the night; much whirling in the head, with heat of the whole body, 1.
Head feels intoxicated; with confusion of the eyes as if he could not see, and sensation of warmth in the face (after seven minutes), 1.
General Head.
Dulness in the head, with painful confusion in the occiput (after two hours), 1.
Stupidity in the head (immediately), 1.
Headache, 12. [50.]
Headache on moving; it seems as if the brain were loose and fell back and forth, 1.
Violent headache, lasting three days, 20.
Sticking headache with stopped coryza, 3.
Sensitive tearings in the head and right eye; as also in a hollow tooth of the left side; with dimness before the left eye and a feeling as if a draft of cold air blew into it, 1.
Forehead.
An empty feeling in the forehead, 3.
Dulness in the forepart of the head as if drunken and reeling; in a moderately warm room, not in the open air (after one hour), 1.
Dull tension in the left frontal eminence, 1.
Headache in the forehead (the whole of the second and third days after taking), 1.
Headache above the eyes, with burning and pressure on them, which compels rubbing and is much increased towards evening, especially in the right, 1.
Painful drawing in the forehead, with nausea, 1. [60.]
Pressive-drawing pain in a narrow line down the middle of the forehead (after three quarters of an hour), 1.
Pressure in the forehead, 1.
Constant sensitive pain beneath the left frontal eminence, as if a dull point were pressing inward; succeeded by intermitting paroxysms of the same pain (first day), .

EYE

Weak, glassy eyes, with great sleepiness, 1.
Very dry eyes, 1.
Feeling in the eyes as though he had wept very violently , with a corresponding expression of countenance, 1.*
Feeling in both eyes as though she had wept much ; everything seems swollen and tense without its being noticeable externally; several days together, 1.*
Burning in the eyes, 1.
After reading a while (even during the day) the eyes pain with a sore burning, and some dimness, so that he was frequently obliged to wink, 1.*
Feeling as though he eyes were smaller than usual (after half an hour), 1. [80.]
Feeling as of biting smoke in the eyes, 1.*
Brow.
Crawling in the brows so that he is obliged to rub them (after a quarter of an hour), 1.
Lids.
Twitching and jerking in the upper lid, 1.
Visible twitching of the lids, with a sensation as if something must be wiped from the right eye (after a quarter of an hour), 1.
Sudden muscular twitches in the lids, with crawling in the left eyebrow, with sensation as if something were in the eye which he must wipe away; very transient (after three-quarters of an hour), 1.
The lids draw together, with running of water from the eyes, 1.
Inclined to press the eyes tightly together from time to time, 1.*
Sensation of heaviness in the upper lid as if it were too heavy, as if the eyes were constantly inclined to close, with dim vision (after half an hour), 1.
Burning in the lids; worse on closing them, 1.
Violent burning in the lids, 3. [90.]
Burning pinching beneath the left lower lid (after nine hours), 1.
On waking at night, she is unable' to open the eyes, because it seems as though a weight were lying upon them; if she forcibly opens them there is tension and pressure, and they can be opened only incompletely after much effort by rubbing and pressing them, .

EAR

Pain in and behind the right ear, like a spasm (immediately), 1.
Cramplike drawing in the concha of the ear and the auditory canals, like earache (after ten hours), 1.
Hearing.
Roaring and noises in the ears, 4. [120.]
Roaring in the head, as from a storm of wind, 4.
After lying down in bed, in the evening, he hears a sound in the left ear like a distant softly sounding ringing, so like a real sound that he can only persuade himself that it is an illusion by completely stopping the ear, when he hears it almost equally loud; it continues until he falls asleep, and only disappears on forcibly fixing his thoughts away from it; several evening, 1.

NOSE

Objective.
Sneezing at different times at 7 P.M. (after eight hours), immediately followed by shaking chill, extending from the back to the feet; the face was warm; the chill affected only the posterior half of the body, though the anterior portion of the chest was also moderately affected; without subsequent heat, 1.
Violent sneezing (soon), 1.
Stopped coryza a few hours after taking; the right nostril is completely stopped, 1.
Stopped coryza, with cold hands and feet, and heat of the face, especially after eating, lasting three days (relieved by Nux), 1.
*Epistaxis of very tenacious, thick, black blood, with cold sweat on the forehead in large drops, 1.
Painful, cramplike drawing from the left frontal eminence to the left side of the bony parts of the nose (after half an hour), 1.

FACE

Dry lips, much inclined to crack, 1.
Smarting of the lips, 1.

MOUTH

Tongue. [130.]
White-coated, very moist tongue; its papillæ were very prominent, 1.
White-coated, though rather dry tongue, in the morning; after breakfast it became clean, 1.
General Mouth.
Dryness and scraping sensation in the mouth, 1.
Dryness in the mouth and very violent burning on one side of the tip of the tongue, as if a blister would appear; very painful on talking or touching the tongue; only on the upper surface of the tongue, 1.
Unusual warmth in the mouth, 1.
Saliva.
Much water in the mouth, and slight biting on the tip of the tongue, as from salt; with sweetish, salty taste, 1.
Taste.
Sweetish taste in the back of the throat, 1.
An offensive, sweetish sour taste in the mouth in the morning after rising; somewhat relieved after rinsing the mouth, 1.
Bitter taste in the back of the throat, 1.
Reproaches made her very angry; she desires to justify herself, but the words stop at her lips; she is now vexed at her silence, and again attempts to talk, but speech refuses its service; she continues to waver in this way and is unable to utter a word in her own defence, though making every effort to do so, 1.

THROAT. [140.]

Sensation in the throat during inspiration, as of sulphur fumes, 1.
A sensation similar to heartburn rises up into the throat, especially after a meal which is eaten with relish (after nine hours), 1.
After eating, a sensation in the throat as if a stopper were forced into it, more on empty swallowing than on swallowing food; it lasts until the next day; wherewith the uvula seems somewhat elongated, with pressive sensation when not swallowing, 1.
On empty swallowing there is a feeling deep in the throat as if a morsel were sticking there and could not go down; he was frequently obliged to hawk, especially in the morning after rising, 1.
Scraping in the throat as after eating very fat food, 1.
Scraping in the throat before and after coughing, 1.
Sharp scraping sensation in the back of the throat which compels hawking, 1.
Scraping rough throat, 1.
Uvula.
Feeling as if the uvula were fallen down when swallowing and when not, 1.

STOMACH

Appetite and Thirst.
Very great canine hunger; she was obliged to eat every moment (first day, in the afternoon and evening), 3. [150.]
Excessive thirst for cold drinks in the afternoon, 1.*
Eructation.
Eructations, 1, 13.*
Tasteless eructations, 1.
Frequent empty eructations in the morning, fasting, 1.
Nausea.
Qualmishness and discomfort, extending from the pit of the stomach into the abdomen, where they moved about as if griping would appear, 1.
Great qualmishness and sensation of weakness in the pit of the stomach, very much relieved in the open air, 1.
Qualmish, nauseated, 1.
Nauseated sensation in chest and throat, as if she would immediately vomit, 1.
Stomach.
Distension in the stomach and abdomen, 1.
Rumbling and fermentation in the pit of the stomach (after a quarter of an hour), 1. [160.]
Sinking pain in the pit of the stomach, 1.
*Sensation as of something living and jumping about in the pit of the stomach, abdomen, arms, and other parts of the body, 1.
Burning in the stomach, 1.
She seems very full after very little food, as if she had eaten too much; with loss of appetite, 1.
Contractive pain in the pit of the stomach, and beneath the sternum, 1.
Drawing in the pit of the stomach, back and forth and up and down (after half an hour), 1.
Some violent stitches in the pit of the stomach (after one hour), 1.
Sensitiveness of the stomach as after taking cold, 1.

ABDOMEN

Hypochondria.
Painless pinching pressure in the right hypochondrium, on every inspiration, as from a broad hard body, 1.
Umbilical.
Some griping above the navel, in the morning, 13.
General Abdomen. [170.]
Movings about in the whole abdomen, with a griping sensation, and from time to time slight urging to stool, 1.
Rumbling in the abdomen, while yawning, 13.
Repeated rumbling in the abdomen, in the morning, while lying in bed, 1.
Slight rumbling, with discomfort in the upper abdomen, 1.
*Sensation internally, in both sides of the abdomen, as if something living were jumping about, with nausea and shivering (after nine hours), 1.
Sensation of emptiness in the abdomen, with complete loss of appetite, 1.
Fulness and pressure in the abdomen, and at the same time in the chest, as if she had eaten too much and too rapidly; though not after eating, 1.
Sensation of distension of the abdomen, in the forenoon, with an empty stomach (after half an hour), 1.
Griping in a small spot on the left side of the abdomen, on a line with the navel, 1.
The child constantly complains of aching in the abdomen; he bends himself together (second day), 3. [180.]
Drawing thirst in the upper abdomen, then in the region of the uterus, 4.
Drawing colic, as if menstruation would appear (first day), 1.
Transient pain, now in the left, now in the right side of the abdomen, as from pressure on a sore spot, 1.
Colic as from taking cold, 1.
Griping jerking in the abdomen, after an ordinary drink of water, 1.
Repeated shocks in the left side of the abdomen, at night, while fully awake, like the movements of a child at the end of pregnancy, and such as she had felt several months previously (after several days), 1.
A painless shock in the upper abdomen, as from something living which jumped upward, .

RECTUM AND ANUS

Sensitive dull stitches on the right side above the anus, 1.
A sensitive, dull, long stitch, near the left side of the anus, from time to time, 1.*
Crawling in the anus, as from threadworms, 1.*
Intolerable cringing in the anus, 1.*
Itching in the anus, that obliges scratching (first evening), 1.

STOOL

Stool earlier than usual, though difficult, 1.
Passage of some blood with the stool, 1.

URINARY ORGANS. [200.]

At night he was awakened by desire to urinate, and a bruised pain with sensation of numbness in the left humerus, upon which he was lying; he found only the lower portion of the body from the middle downward covered with sweat; on rising he was dizzy, staggered, and he had a sensation as though a cold wind were blowing upon the sweaty parts, together with a feeling in the feet as though a cold sweat were trickling down, 1.

SEXUAL ORGANS

Male.
Intermitting sharp sticking from the genital region up into the right hypochondrium, as if a knife were forced in this direction with sudden thrusts, piercing farther each time, and becoming more severe (after six hours), 1.
Excitement of sexual desire, 1.
Female.
Fatal hæmorrhage of the uterus, especially after parturition, 7.
*Metrorrhagia on the slightest movement, 4.
Sensation as if menstruation would appear, with colic and pressing towards the genitals (after a few hours), 1.*

RESPIRATORY ORGANS

Larynx, Trachea, and Bronchi.
Stitches in the air-passages, more towards the posterior portion (after four hours), 1.
Voice.
Hoarse voice, with some cough (second morning), 3.
Much hawking, on account of collection of large quantities of mucus, which makes the voice rough and scrapy, 1.
Cough and Expectoration.
Much cough, 1. [210.]
Paroxysm of dry cough, as from constant and excessive irritation in the trachea, 1.
Very violent attack of exhausting dry cough , relieved by laying the hand on the pit of the stomach, 1.*
Expectoration of large masses of easily detached mucus, with slight cough, 1.
Respiration.
The breath, which is usually sweet, has a very offensive sickly odor, 1.*
Slight rattling on inspiration, followed by mucus in the throat and hoarseness; the mucus immediately disappears on hawking, 1.
Dyspnœa, 1.
Frequent choking, caused by tickling in the upper part of the trachea, during inspiration, 1.

CHEST

Heaviness of the chest frequently obliges him to take a deep breath, 1.
Aching in the whole of the chest, 1.
A sudden transient ache in the lower portion of the chest and pit of the stomach, with slight nausea (after three-quarters of an hour), 1. [220.]
Oppression of the chest (after eight hours), 1.
A kind of oppression that renders complete yawning difficult; it can only be accomplished after several attempts (after ten minutes), 1.
Sides.
Sticking in both sides of the chest, rather externally, which afterwards extends farther forward and becomes a burning, without influencing respiration or motion (after one hour), 1.
Short sticking in the right side of the chest, 1.
Dull stitches in the left chest, 1.*
*A kind of jumping, as from something alive in the lower portion of the right half of the chest, as if beneath the ribs, 1.
Some dull shocks beneath the right short ribs, near the pit of the stomach, and on inspiration an aching there, as it a pain were caused by breathing (after two hours), 1.
Jerking-like shocks in the left side of the chest, feeling as though they would take away the breath, 1.
A peculiar jerking pain in the left side of the chest, internally, as if it were being drawn at intervals towards the back by a thread, 1.

HEART AND PULSE

Præcordium.
Warmth about the heart, with anxiety and some oppression of breath, so that she cannot breathe deeply, with inclination to take a deep breath; she feels relieved every time after frequent yawning, 1. [230.]
Sensation of great emptiness in the præcordial region, 4.
Drawing in the præcordial region, extending to the stomach, like colic, 1.
Stitches beneath the heart, aggravated on inspiration (after two hours and a half), 1.
Heart's Action.
Palpitation; anxiety at the heart, with a sensation of weakness extending thence through the whole abdomen, and continuing down to the soles of the feet (second day), 1.
Very frequent palpitation, 4.

NECK AND BACK

Neck.
External swelling of the neck (inflatio colli), 6.
Painful stiff sensation in the neck, on moving, 1.
Sudden drawing in the left side of the neck, internally and externally, at the same time extending into the ear (after a quarter of an hour), 1.
Back, Lumbar.
Pains in the small of the back, in the morning and at night, in bed, on motion, 3.
Tearing pain in the small of the back, worse on breathing (after one hour), 1.
Sacral. [240.]
A slow dull stitch, extending from time to time from the anus through the sacral region and into the left inguinal region, where it remains as an aching, aggravated by inspiration, gradually disappearing, 1.

EXTREMITIES IN GENERAL

Cracking of the joints, not without a painful sensation on moving them, 1.
Loss of power in different limbs; even slight motion caused a bruised sensation, especially in the hip-joint, 1.
Falling asleep of an arm, hand, and foot, 1.

SUPERIOR EXTREMITIES

Falling asleep of both arms, 1.
Falling asleep of the arms and hands, at night, in sleep; she was awakened by the crawling pain (after eight hours), 1.
Falling asleep of both arms and hands, with a kind of immobility (after a quarter of an hour); recurring several times during the day and lasting half an hour, 1.
The arms, especially the forearms, feel very heavy, and if as bruised, 1.
Dull pain, with sensation of paralysis, in the left arm, 1.
Bruised pain, immediately, on slight motion of the arms, 1.
Shoulder. [250.]
Muscular twitchings on the top of the shoulder, in the morning, while lying in bed; both visible and felt, 1.
Cracking in the shoulder-joint on moving it suddenly, with sensitive pain as if the arm would be dislocated, 1.
Feeling in the left shoulder-joint, as though the arm would be easily dislocated, as if it were lying loose in the joint (after a few days), 1.
At times, on moving the upper arm, a pain, within the shoulder-joint, as if the head of the humerus were lying loosely within the capsule of the joint and would be dislocated, 1.
A tensive aching in the shoulder-joint, with cracking in it, on moving the upper arm outward, 1.
Bruised sensation in both shoulders, 3.
Some sensitive shocks in a small spot on the back of the shoulder, 1.
Elbow.
Sudden, violent tearing pain in the right elbow-joint, soon disappearing, 3.
Forearm.
A pain in the right forearm extending obliquely to the thumb, 1.
A slight pain in a small spot on the left forearm, not far from the elbow, whereby the elbow is spasmodically and involuntarily thrown upward, causing him to start (after nine minutes), 1.
Hand. [260.]
Dull pain in the right hand, 1.
A kind of intermitting drawing, so that every intermission causes a transient burrowing in a small spot; worse when resting the forearm upon anything, whereby a benumbing warmth spreads over the hand, .

INFERIOR EXTREMITIES

Sensation of paralysis in the legs, after walking, especially in the knees and metacarpal joints, so that farther walking became very difficult, and even standing was irksome, 1.
Hip.
Violent cracking, like a report, in the right hip-joint, on stretching out the thigh and moving it outward, 1.
Thigh.
A sensation of weakness of the thigh extending down to the knee, especially while sitting (after half an hour), 1.
Aching in the lower surface of the thigh, after sitting a long time, 1. [270.]
Sudden shuddering sensation in the nates while sitting, as from a violent fall upon them, 1.
Knee.
On stooping down, immediately an audible noise in the knee-joint, with a sensation not entirely painless, 1.
The knees knock under even while standing, 1.
Weariness in the knees, even to sinking down, 1.
A painful tension in the knees on sitting down; on standing it becomes a painful sensation as if the joints were dry from want of synovial fluid, and as if they would crack and creak on moving them, 1.
Intermitting, very painful drawing in the bent knee, 1.
Tearing in the knees, extending down to the malleoli, where it then continues aching and drawing back and forth, so that she is frequently obliged to change the position of the feet at night, 1.
Leg.
Great weariness of the lower legs in the bones, in which there is a painful tingling sensation, extending from above downward, in the evening; it is felt less during motion; but more, immediately after motion; it is, however, somewhat relieved by rest, 1.
The legs feel bruised, 1.
Bruised sensation in the calves, as if he would stumble over his own legs, 1. [280.]
Smarting in the calves, soon followed by tearing in them, 1.
Ankle.
At one time sudden, at another slow, transient, intermitting, dull or very acute pain in a small spot above the malleolus, as if in the periosteum (after eight hours), 1.

GENERAL SYMPTOMS

Objective.
Distended veins, with a sensation of heat, without much increase of temperature, 1.
Anxious trembling through the whole body, 1.
Every evening, spasms, with delirium, alternating with tender humor, wildness, and outbreaks of rage, with inclination to bite, 1.
Lassitude, indolence, sleepiness, 1.
Weakness in the whole body, hands, and feet, 1.
Weakness, even to sinking down, with sensation as if sweat would break out over the whole body, and rapid pulse, 1.
In the morning, excessive weakness, yawning, weariness; she felt better on going into the open air; worse in the room, 1.
Extreme exhaustion, with sensation as though general sweat would break out; he was scarcely able to stand, constantly desired to sit and lie, and even then continued to feel the lassitude (after four hours), 1.
Excessive prostration, with weakness and weariness in the evening, after a very simple and moderate meal, as if he had made the most difficult physical exertion, with great sleepiness and sleepy pressure upon the eyelids, with a feeling as if they were swollen; literary occupation removed this weakness, 1. [300.]
Frequent attacks of faintness, 4.
She lay as though in apoplexy (from smelling of it), 8.
Subjective.
Sensation of weakness and great indolence in the whole body, even with a sensation of approaching faintness, 1.
Uneasiness in the blood, with palpitation of the heart, 3.

SKIN

Objective.
Scarlet redness of the whole body, 1.
Circumscribed red spots in the face, which burn, 1.
Subjective.
Crawlings here and there over the whole body, frequently and in rapid succession, relieved by scratching, 1.
Formication in the right index finger, 1.
Itching on several parts of the body, 1.
Itching on the right side of the scrotum (first and second evenings), 3. [310.]
Intermitting painful itching on the left frontal eminence, 1.

SLEEP AND DREAMS

Sleepiness.
Yawning and chilliness, with burning of the lids and thirst for cold drinks, without drinking much after supper, 1.
Frequent yawning, 13.
Frequent yawnings in rapid succession (after ten minutes), 1.
Excessive yawning, and inclination to sleep, 12.
Sleepiness, 1.
Sleepiness; immediately after dinner great inclination to sleep, with creeping chills, 1.
Excessive sleepiness, with yawning; she constantly desired to sleep; very much yawning during the day, 1.
He sings during sleep, 1.
Sleeplessness.
Uneasy sleep, with frequent waking; he tosses about, but falls asleep again, with vivid dreams, 1. [320.]
Frequent waking at night, 13.
He awoke unusually early, and thought it was very late, 1.
He awoke in the morning earlier than usual, and then remained more wide awake than usual, 1.
Dreams.
Many confused and even frightful dreams of various things at night, as for example, what had been spoken or done through the day, of fires and the like, 1.
In her sleep she seems to hurry for a distant place, but is unable to reach it however much she exerts herself, 1.

FEVER

Chilliness.
Chilliness (after half an hour), 1.
Chilliness the whole afternoon, with some thirst, 1.
Chilliness at 9 P.M. (after four hours); although the room was warm, he seemed to be in an unheated room; this sensation increased to a shaking chill over the whole body, with paleness of the face and ice-cold hands, 1.
Creeping chills along the back, across the shoulders and then down the arms, with gooseskin and frequent yawning (after five minutes), 1.
Sensation of coldness in the back (after two hours and a half), 1. [330.]
Sudden decidedly cold sensation in the left side of back, as if he had been dashed with cold water; lasting a long time, 1.
Cooling of the hands; a sensation of a wind extending up the arm, 12.
Heat.
Sensation of warmth creeps rapidly over the body (after a quarter of an hour), 1.
She is attacked with great heat, so that it seems to crawl in the skin, 1.
She was attacked with very violent heat over the whole body, chiefly in the head, with redness of the face and great thirst, without much dryness of the mouth; lasting a few hours, towards evening (second day), 1.
General sensation of heat, with prickling in the skin, a though sweat would break out, with, however, a normal, almost cold temperature, 1.
Orgasm of blood, as if everything was moving in the body, without much noticeable heat, 1.
Heat of the face without marked redness, 1.
*Heat in the face; it seems very hot in the face and in front of the head, 1.
Glowing heat in the face in the morning after walking, 1.

CONDITIONS

Aggravation.
( Morning ), After waking, headache; pain in eyeball; feels worse ; coated tongue; after rising, taste in mouth; after rising, on empty swallowing, feeling in throat; fasting, eructations; griping above navel; while lying in bed, rumbling in abdomen; in bed, on motion, pains in small of back; while lying in bed, twitchings on top of shoulder; weakness, etc.; after waking, heat in face.
( Forenoon ), Sensation in abdomen.
( Afternoon ), Towards evening, headache before eyes; thirst for cold drinks; towards evening, sensation in lower abdomen; chilliness, etc.; heat, etc.
( Evening ), Vacillating mood; ill-humor; by the light, sensation in eyelids, etc.; after lying down in bed, sound in ear; felt less during motion, but more immediately after it, and somewhat relieved by rest, weariness in lower legs; spasms, etc.; prostration, etc.
( Night ), Whirling in head, etc.; on waking, weight on eyelids; shocks in abdomen; desire to urinate, etc.; pains in small of back; falling asleep of arms, etc.; tearing in knees, etc.
( Closing eyes ), Burning in lids.
( After dinner ), Immediately, inclination to sleep, etc.
( After eating ), Heat of face; more on empty swallowing, sensation in throat.
( During inspiration ), Sensation in throat; pressure in right hypochondrium; choking; aching beneath ribs; stitches beneath heart; pain in small of back; stitches through sacral region.
( After a meal eaten with relish ), Sensation rising into throat.
( On moving ), Headache.
( On reading ), Veil before eyes.
( After rising from lying down ), Dizziness, etc.
( In room ), Feeling of water in eyes.
( Sitting ), Weakness in feet, etc.; smarting in soles.
( After supper ), Yawning, etc.
( On swallowing ), Pain in side of head.

SUPPLEMENT: CROCUS. Authorities.

13 , Wm. Alexander, M.D., Experimental Essays, London, 1770, effects on himself; 14 , E. W. Berridge, Am. Journ. Hom. Mat. Med., New Ser., vol. v, 1876, p. 245, Mrs. --- put 7 drops of 3d in a glass of water, and took a teaspoonful every three hours, for three or four days, for a chronic affection of the eyes; same symptoms a second time of this medicine. [340.]

While taking it throbbing pain came on in first left upper incisor, extending round to all the teeth in left upper jaw (all decayed); worse by any one walking across the room or by opening mouth; better by quiet; the throbbing was as if the blood were being pumped through too quickly; it caused throbbing in forehead and vertex. The toothache was followed by watery diarrhœa, generally about 4 A.M., once about 10 P.M., and before and during the stool there were sharp cutting pains in abdomen, from sides of abdomen to centre, making her bend forwards, which relieved the pains; for three or four weeks the toothache and diarrhœa alternated; the toothache would last all day, being bad for an hour; the diarrhœa generally from 4 A.M. to 1 or 2 P.M.; generally had one or the other every day. The hair fell off temples and sides of head, 14.
10 grains of Saffron, made into a paste with a little bread, was taken in the morning on an empty stomach. It made no alteration on the mercury in the thermometer at my stomach; it did not affect my pulse, nor operate in any manner that I could be sensible of. The next day I took 1 scruple of Saffron, which did not alter the height of the mercury, though my pulse soon after was more frequent by two or three strokes in a minute. This I imagine was accidental, as I felt no effect from my dose. Some days after I took 2 scruples. An hour afterwards I found the mercury in the thermometer at my stomach risen one degree. Upon this I expected that my pulse would be risen also, but was very much surprised to find it fallen from 72 to 66; and still more to find that it continued about 66 and 67 all the rest of that day. Some days after I took 4 scruples. This had no manner of effect, either on the mercury in the thermometer at my stomach or my pulse; so that I concluded the remarkable diminishing of it in the last experiment had not been owing to any effect of the Saffron, but to some other cause. I expected it would have perhaps tinged my urine, the color of which I examined carefully from time, without being able to discover the least alteration in it. The excrement, however, that I passed, was very strongly tinged with it, 13.

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