Kali Aceticum

K

Preparation , Solutions in alcohol or water.

Authorities.

1 , Vogt took nine teaspoonfuls of Liq. Kali Acet. first day, ten teaspoonfuls second day, same third day, seven teaspoonfuls fourth day, Bœcker's Beitræge; 2 , second series of experiments, "by one more sensitive to the action of the drug than Vogt." Huekenbeck took two teaspoonfuls at 8 and 11 A.M., one teaspoonful at 1, 3, and 9 P.M. (first day); repeated doses aggregating eleven spoonfuls (second day); in all ten spoonfuls (third day); in all fifteen spoonfuls (fifth day); and twelve spoonfuls a day (sixth, seventh, and eighth days); 3 , Cattell, Br. J. of Hom., 11, 349, symptoms from Month. Journ., May, 1850, and Med. Times, Oct. 1849; 4 , Dr. Golding Bird's experiments, effects on a young lady, Bost. Med and Surg. J., 1862, p. 133.

HEAD

• Confusion with pains in the head, transient (first day), 2.
• Headache about 4 P.M. (eleventh day), 2.
• Dull headache in the morning (fourth day), 2.

NOSE

• (Catarrh with some hoarseness, on which account the proving was suspended, though I was uncertain whether or not it was the effect of the drug), (fourth day), 1.

STOMACH

• Constrictive dull pain in the stomach, extending to low down in the abdomen, gradually disappearing after two hours (first day), 2.
• Dull, pressive, pinching and constrictive pain in the epigastric region, coming on a few minutes after each dose, and lasting an hour (first day), 2.

ABDOMEN

• Pains in the region of the umbilicus, lasting without cessation till going to bed, when they suddenly disappeared, and I was able to sleep through the night (first day), 2.
• Unnatural distension of the abdomen after supper (third day), 2.
• Griping, 3. [10.]
• Griping pain in the abdomen, transient (second day), 2.
• Gnawing pain in the abdomen (third day), 2.
• An indefinite gnawing pain in the abdomen, lasting an hour in the afternoon (fifth day), 2.
• Gnawing sensation in the abdomen at 9.15 A.M., which became painful after fifteen minutes and lasted till evening (sixth day), 2.

RECTUM AND ANUS

• Discharge of hæmorrhoidal blood several times during the day (second day), 1.

STOOL

• Diarrhœa, 3.
• Two evacuations (second day), 1.
• Two stools in the evening (fifth day), 2.

URINE

• Urine much increased in quantity and very watery, 3.
• 16 ounces of urine in twenty-four hours, containing 416 grains of solids; after 3 drachms had been taken in the course of twenty-four hours she passed 46 ounces of urine containing 782 grains of solids, with an excess of 72 grains of urea over the amount in the 16 ounces of urine passed when no medicine was taken, 4. [20.]
• While taking the drug there was an average daily increase of 208 grammes of the urine; an increase of 206 grammes of the aqueous portion of the urine; an increase of 1.98 gramme of the solid constituents; decrease of 3.80 grammes of the urea; decrease of .008 gramme of the uric acid (the daily average before taking the drug being .008 gramme, but while taking there was absolutely none); an increase of 6.94 grammes of the inorganic salts; decrease of .54 of phosphatic earths; decrease of .06 of phosphate of lime; decrease of .27 of phosphate of magnesia; decrease of 1.14 gramme of volatile salts and extractives; the diminution of the earthy phosphates, of the phosphate of lime and phosphate of magnesia is established; that the inorganic salts are increased seems to rest upon the fact that the prover was taking an inorganic salt; it is noteworthy that the amount of urea was only very slightly diminished, though the development of the carbonate of ammonia in the urine showed that there was active decomposition of the urea and uric acid, thence it is very probable that the quantity of urea is increased by acetate of potash, 2.
• During the proving there was a diminution in the amount of urine 36.25 grammes; a diminution of the aqueous portion of the urine 50.13 grammes; an increase of the solid constituents 13.88 grammes; a decrease of the urea .76 gramme; an increase of the uric acid .20 gramme; increase of mucus .16 gramme; increase of inorganic salts 14.47 grammes; decrease of the phosphatic earths 1.50 gramme; decrease of volatile salts and extractives .20 gramme, 1.
• It was noticed during the proving that the urine evolved ammonia, which probably arose from the decomposition of the nitrogenous constituents of the urine, 1.
• The normal specific gravity of the urine 1.0116, reaction acid; specific gravity 1.015, reaction alkaline (first day); specific gravity 1.013, reaction alkaline (second day); specific gravity 1.020, reaction alkaline, somewhat turbid (third day); specific gravity 1.014, reaction alkaline (fourth day), 1.
• Specific gravity of urine 1.019, reaction alkaline, (first day); specific gravity 1.018, reaction strongly alkaline, of a peculiar sweetish odor (containing no sugar), (second day); 1.021, reaction alkaline, odor alkaline, of a yellowish color, turbid, without sediment (third day); specific gravity 1.019, reaction alkaline, odor alkaline, of a deep yellow, saturated color, somewhat turbid (fourth day); specific gravity 1.020, reaction alkaline, odor alkaline, of a yellow color, turbid (fifth and sixth days); specific gravity 1.022, reaction strongly alkaline, odor alkaline, color yellow, turbid (seventh day); specific gravity 1.026, reaction strongly alkaline, odor strong alkaline, not quite clear; in the morning the urine had no sediment, but after twelve hours it deposited small quantity of earthy phosphates (eighth day); specific gravity 1.027, reaction very strongly alkaline, odor alkaline, quite clear, whitish sediment, of a yellow color (ninth day); specific gravity 1.030, reaction very strongly alkaline, odor alkaline, turbid, or a whitish-yellow color (tenth day); specific gravity 1.024, reaction very strongly alkaline, odor alkaline, turbid, of a whitish-yellow color (eleventh day), .

EXTREMITIES IN GENERAL

• Great weariness of all the limbs, with some headache (tenth day), 2.
• Extreme weariness and trembling in all the limbs, in the morning (fourth day), 2.

INFERIOR EXTREMITIES

• The weariness in the lower limbs and the dull headache disappeared half an hour after the afternoon nap (fourth day), 2.

GENERAL SYMPTOMS

• Dropsy (?), 3.
• Trembling and anxiety in the whole body, of transient duration, soon (first day), 2.

FEVER. [30.]

• Profuse perspiration, which was very offensive, during a walk of two hours (seventh day), 2.
• Much perspiration on the head, especially from 11 to 1 o'clock (fourth day), 2.

CONDITIONS

• Aggravation.
• ( Morning ), Dull headache.
• ( Afternoon ), About 4 o'clock, headache; weariness, etc., in limbs.
• Amelioration.
• ( Afternoon nap ), Weariness in lower limbs, etc.