Simaba cedron, Planch.

Nat. order , Simarubaceæ.

Preparation , Triturations and tincture of the seeds.

Authorities.

1 , Mr. G. B., aged 24, took the 6th dil. every morning for four days; on the fifth day, night and morning (from Teste, Systématisation de la Mat. Méd., p. 561); 2 , Mad. T., aged 27, took the 6th, night and morning for two days (ibid.); 3 , Mlle. Marie C., aged 17, took one dose of the 6th for a neurosis of the heart (ibid.); 4 , Dr. Jno. N. Casanova, several provers, male and female (undistinguished); "the symptoms recorded in the first series of my experiments, while in South America, were produced with ponderable small and repeated doses, sometimes of the powder, sometimes of the aqueous solution.... Those recorded in my late investigations, since my return to Europe, were obtained with different potencies," Month. Hom. Rev., vols. 5 and 6; 5 , Dr. J. Douglass, N. Am. J. of Hom., 8, 120, took the tincture, 1 to 2 drops, on the first, second, and fourth days; 6 , ibid., proving of Miss C., took 3 drops of tincture; 7 , ibid., Mr. W., took 1 drop of tincture; 8 , Mrs. M., ibid., took 1 drop of tincture; 9 , ibid., Mrs. B., took 2 drops of tincture two evenings in succession; 10 , Dr. Stennett's provings, W. Hom. Obs., 2, 11, A. W. W., took the tincture from the bruised nut, repeated doses of 5 to 60 drops; 11 , ibid., proving of S. M. P., repeated doses of 5 to 100 drops of saturated tincture; 12 , ibid., proving of S., with 10 to 300 drops of the tincture, and 5, 15, 80, 160, and 200 grains of the powdered nut.

MIND

Emotional.
Gloomy, depressed spirits, 4.
Disposition to weep, 4.
Inquietude and excessive anguish, 4.
Anxiety (after nine hours), 3.
Dread of friends (in females, particularly), 4.
Intellectual.
Torpor of the mental faculties and uneasiness, 4.
Dulness of the senses, 4.
Did not know her acquaintances, 6.
The greater part of the mental symptoms were repeated in the morning and aggravated at night, 4.

HEAD

Vertigo. [10.]
11 A.M., slight dizziness (third day), 6.
On rising from bed, dizzy, and could not see to light a candle, and could not tell when it was lighted, 6.
General Heat.
Bending the head backwards, with pressure on the occiput and parietal regions, as if those parts were going to burst, 4.
Head dull and heavy in the evening, 4.
Headache, especially deep in the orbits, obliging him to shut his eyes, and extending to the occiput (second day), 1.
Headache worse in open air (about 9 P.M.), 2.
Distensive headache, increased during the night, 4.
Head felt as if swollen, 5.
Whole head feels swollen and heavy, most on right side (after two hours and a half), 5.
Forehead.
Pressive pain above the eyes, as from a band compressing the forehead, 2. [20.]
Throbbing pain in head, commencing in temples, extending around the forehead, 2.
Temples.
Temporal arteries enlarged, 4.
Pulsations in temporal arteries (after half an hour), 5.
Pain in temples (second day), 6.
Slight pain in temples (15 drops), 10.
Continued pain in temples, passing from side to side (60 drops), 10.
Pressure at the right temple, causing a dull pain in the whole right side of the head, disappears wholly towards noon, 2.
Throbbing in temples, 9.
10 A.M., throbbing in temples (third day), 5.
Throbbing in temples, increasing to pain, 6. [30.]
Throbbing in temples, increasing to pain, extending around and over the eyes, 8.
Beating in temples, increasing to pain and extending over ears (after half an hour), 7.
Pulsating sensation in temple, and a twisting pain behind right ear, changing to a dull pain, and extending to the temples (after half an hour), .

EYE

Eyes red and protruding, with pressive pain extending to forehead, 4.
Redness of the eyes, and itching of the inner and outer surfaces of the eyelids (during fever), 3.
Eyes feel dry when exposed to air (second day), 5.
Alternate dryness and smarting of the eyes, with moisture, 9.
Eyes felt swollen, 6.
Smarting in the eyes, especially when closing them (during fever), 1. [50.]
Smarting and burning in eyes, with great discharge of tears (50 drops), 12.
Itching of the eyes, 2.
Brow, Etc.
Pain across the eyes, from temple to temple, 6.*
*Severe shooting pain in over left eye (15 drops, after three hours and a half), 12.
Lids.
Eyelids injected, bright red, and painful when pressed, 4.
Spasmodic twitching of the muscle levator palpebræ superioris, observed in two provers, during three successive nights, 4.
Enlargement of the Meibomian glands and conjunctiva, 4.
The left eyelid seemed dried to the ball (second day), 5.
Burning sensation in upper lids (after two hours and a half), 5.
Lachrymal Apparatus.
Profuse secretion of tears, which instantly ran down face (160 grains), 12. [60.]
Acrid tears, which seemed to scald the cheeks as they ran down (40 drops), 12.
Conjunctiva.
Conjunctiva inflamed and dry (second day), 5.
11 A.M., redness of whites of eyes (second day), 5.
Pupil.
Pupils fixed and dilated, 4.
Dilated pupils (after nine hours), 3.
Vision.

Bell ., 4.

Dimness of sight (after nine hours), 3.
On rising from bed, could not see to light a candle, and could not tell when it was lighted, with dizziness, 6.

EAR. [70.]

Pain over ears (after twenty minutes), 5.
Pressure over the ears (after half an hour), 5.
Singing in ears, as of crickets, 5.
Buzzing of the ears towards noon, 4.
Hardness of hearing at night, 4.

NOSE

Great secretion of glassy-looking mucus in nose (60 drops), 11.
Profuse discharge of thin, clear, acrid mucus from nose (50 drops), 12.

FACE

Perhaps there was throughout the proving a little puffiness of the face, 2.
Cheeks red and burning at night, pale and cold in the morning, 4.
Pressing or tearing pain in one or both cheeks, with occasional shooting under the orbits, 4. [80.]
Dry lips, which have to be moistened frequently (second day), 1.

MOUTH

Teeth.
Pain in a decayed tooth for the first time, 8.
Tongue.
Tongue coated yellow, even to the tip (second day), 5.
Tongue coated yellow, on rising in morning (third day), 5.
Slightly yellowish coat far back on tongue, 5.
Pricking of the tongue early in the morning, which goes off after eating, 4.
About 5.30 P.M., pricking on the tongue, itching of the eyes; half an hour later, chilliness, with heat of the face, pale hands, feet and tip of nose cold (seventh day), 2.
About 5 P.M., intolerable pricking-itching of the tongue, so that she had to keep rubbing it against the palate (second day), 2.
General Mouth.
Dry mouth, with thick, viscid saliva (after nine hours), 2.
Mouth dry, with viscid saliva when talking, 4. [90.]
Burning in mouth, throat, and stomach, 12.
Burning in mouth, fauces, œsophagus, and stomach, as if mucous membrane was raw (60 drops), 10.
Burning and smarting in mouth and fauces (5 drops, after ten minutes), 10.
Burning and scraping feeling in mouth and throat, with profuse discharge of thin saliva (10 drops, after a few minutes), 12.
Tingling sensation in mouth, as from the shock of a galvanic battery (10 drops, after one hour), 12.
Saliva.
After talking, the saliva becomes white and thick, like cream (fifth day), 1.
Saliva becomes sour at night, 4.
Profuse secretion of saliva, which had a metallic taste (75 drops), 12.
Taste.
Bad taste in mouth (15 drops), 10.
Nasty taste of mouth (second day), 7. [100.]
Nasty, sickish, bitter taste of mouth (second and third days), 5.
Sickish, slimy taste (second day), 5.
Sour taste (second day), .

THROAT

Prickling and tingling in throat and fauces, which seemed to extend some way down the œsophagus (15 drops), 10.
Constriction of throat, almost preventing her from swallowing saliva (after nine hours), 3.
Difficulty of swallowing, 4.

STOMACH

Appetite and Thirst.
Loss of appetite (third day), 1.
Appetite is impaired as the proving progresses. [110.]
Thirst at night and during the febrile symptoms, 5.
Thirst, and craves only warm drinks (during fever), 4.
Thirst, and desire for cold water at noon, and warm during night, 4.
Excessive thirst (second day), 6.
Want of thirst, during the chills, 2.
Aversion to cold water in the evening, 4.
Eructations.
On rising in morning, gulping up of a bitter wind, with dull pain in temples (third day), 5.
Nausea.
Slight nausea (40 drops), 12.
Stomach.
Distension of the stomach and disposition to nausea, generally aggravated by rest, but relieved by walking and by eating, 4.
Sensation of heat and fulness in stomach, 4. [120.]
Sensation, as of a stone, on the stomach, 6.
Rolling pain in stomach, 6.

ABDOMEN

Hypochondria.
Rose with pain in region of liver (third day), 6.
Stitches in the spleen and in the liver, 4.
General Abdomen.
Inflated abdomen, 2.
Abdomen hard and distended, towards evening, 4.
Borborygmi in left side of abdomen, 2.
Flatulence in morning, with slight colic and occasional discharge of fetid wind, 4.
Colic during dinner (second day), 2.
Colic and cramps in small intestines, 12. [130.]
In the morning, flatulent colic, with emission of fetid flatus (fifth day), 1.
Pain in bowels, extending through small intestines (30 drops), 1.
Pain and colic in small intestines (60 drops), 10.
At noon, sharp pains, alternating in cæcum, liver, and spleen, running from one to the other (third day), 5.
On getting warm in bed, flying pains in the region of the ascending colon, liver, and spleen, kept him awake most of the night, 5.
Severe, sharp griping-cutting pains in lower part of abdomen (975 drops), 12.

RECTUM AND ANUS

Unsuccessful urging to relieve the bowels, 4.
Ineffectual urging to stool (second day), 2.

STOOL

Diarrhœa.
Copious stool, with excessive tenesmus (third day), 5.
A rather copious evacuation in the evening (fourth day), 1. [140.]
Whitish stools, mixed with fragments of a mass similar to clotted milk, in some provers, 4.
Yellowish, loose evacuations, three days after taking large quantities of

Cedron , in some provers, 4.

Almost immediately after slight colic, a copious evacuation of a substance that looked like curdled milk, white, with a slightly yellowish tint (from chewing the nut as an antidote to the bite of a ).
Constipation.
Constipation, 4.
Constipation (third day), 1.
Constipation (fourth day), 2.

URINARY ORGANS

Kidneys.
Pain in kidneys, 12.
Pain in kidneys (60 drops), 10.
Slight pain in kidneys (10 drops), 12.
Severe pain in kidneys, soon followed by a profuse discharge of clear transparent urine (15 drops, after one hour), 12. [150.]
Excessive pain in kidneys (160 grains), 12.
Excessive pain and burning feeling in kidneys and along ureters, as if boiling water was pouring through them (40 drops), 12.
Severe pain in region of kidneys, with a profuse secretion of urine, smarting and burning in urethra (50 drops), 10.
Urethra.
In a young man, a discharge like gonorrhœa, lasting three days, and ceasing spontaneously when the medicine was stopped, 4.
Thin, gleety discharge day and night, with feeling of ants crawling over body (160 grains), 12.
Feeling as if a drop of urine were in the urethra, or a constant dropping from it (60 drops), 10.
Pain and burning in urethra, when not voiding urine (60 drops), 10.
Burning in urethra (160 grains), 12.
Burning in urethra and along ureters, 12.
Frequent but ineffectual urging to urinate, 4. [160.]
Cessation of a frequent urging to urinate, which had lasted about a week, 2.
Micturition.
Increased secretion of urine (60 drops), 11.
Profuse secretion of urine, 12.
Profuse secretions of urine (60 drops), 10.
Profuse secretion of urine, with numb, uneasy feeling in urethra (60 drops), 11.
Profuse discharge of watery urine (second day), 2.
Profuse discharge of light-colored urine (30 drops), 11.
Frequent emissions of large quantities of pale urine, 9.
Scanty urine, 4.
From the first, urine scanty and deep-colored, 5.

SEXUAL ORGANS

Male.
Firm erections in morning (second day), 7.
Woke with firm erections in morning, 5.
Firm erections all night (second day), 5.
Sexual desire, with erections, in several men, 4.
Female.
Genital excitement at daybreak, with a discharge like leucorrhœa, and swollen mammæ, with some pain (in two married women), 4.

RESPIRATORY ORGANS. [180.]

Profuse secretion of clear thin mucus in bronchi (40 drops), 12.
Larynx constricted and tender, 4.
Difficult respiration, with partial loss of voice, recurring at different intervals, 4.

CHEST

Oppression on chest, 12.
Oppressive pain in the chest, extending now and then to the back, with frequent inclination to sigh and draw a deep breath, 2.
Pressure on chest, as from a heavy weight (40 drops), 12.
Pain under floating ribs and under right scapula (60 drops), 11.
Sharp darting-cutting pains under both ribs; this pain continued four hours (60 drops), 11.
Pain in right side, which lasted for three hours (after half an hour); next day, pain in side and under scapula returned at 3 P.M., although no medicine taken; next day but one (no medicine taken), pains returned at 4 P.M., but less severe (100 drops), 11.
Oppression of the chest and throbbing of the heart (in nearly all the provers in whom febrile paroxysms were developed), 4.

HEART AND PULSE. [190.]

Palpitation of the heart and hurried breathing, with headache (during fever), 4.
Increase of pulse, 9.
Pulse increased twelve beats per minute, firm, full (after half an hour), 7.
Pulse increased fifteen beats per minute (after twenty minutes), 5.
Pulse increased fifteen per minute, very full (after half an hour), 5.
Pulse increased fifteen beats per minute (in a quarter of an hour), 8.
Pulse somewhat accelerated (65 drops), 12.
Pulse accelerated about ten beats per minute (5 drops, after ten minutes), 10.
10 A.M., pulse 90 (third day), 5.
Pulse 90 (after half an hour), 6. [200.]
In morning, pulse 95, full (second day), 5.

NECK AND BACK

Pain in the back and loins, on getting up in the morning (seventh day), 2.
Pain under scapula and in pelvis (5 drops after three hours), 11.
Uneasy feeling in lumbar region, with feeling as if there was a drop of urine in glans penis (60 drops), 10.

EXTREMITIES IN GENERAL

Numbness of hands, arms, and legs, 12.
Smart rheumatic pains in all the joints of the limbs, 9.
At 10 P.M., sharp flying pains in all the joints of the extremities, worse in feet, particularly first great toe joint (third day), 5.
Arthritic flying pains continued more or less for more than four weeks, most in feet and hands, some in elbows, more in knees and hips, but most troublesome in the first joint of great toes; pains relieved by motion and cold, before soreness of the joints came on, when they were increased by motion and cold; worse at night, 5.
Transient lancinating pain in the joints, especially in the right elbow (seventh day), 1.
The pains in the limbs seem to be in the cartilages of the joints particularly in the first joint of the great toe, and streaking up the bones, 5.

SUPERIOR EXTREMITIES. [210.]

Painful weariness in the shoulders (second day), 2.
Pain in the elbow and right forearm, as if from a blow, lasting a quarter of an hour, 2.
Passing pains in elbows and forearms, with a cold sensation extending to the hands, towards noon, 4.
Sharp cutting pain in both elbows (5 drops, after three hours), 11.
Numbness and dead feeling in right hand and forearm, so that he could not hold his pen (15 drops, after three hours and a half), 12.
Pains (when not febrile concomitants) relieved by friction, 4.

INFERIOR EXTREMITIES

Numbness in right leg (15 drops, after three hours and a half), 12.
Legs felt as if very much enlarged (65 drops), 12.
Lancinating pains in the joints of the knees, 4.
Contracting pains in the legs, as if produced from contusion, in the evening; these, and the pains in the knees, were relieved by friction, when not followed by chills or shivering of the whole body as precursors of fever, 4. [220.]
Sort of jerking and twitching of tendons of legs, in tendo Achillis and in right foot (150 drops), 12.
Sharp lame pain in right ankle (second day), 7.
Swelling of feet, with extreme pain in all the joints, 9.
In the forenoon, pain in the heel (which?), as if an abscess was forming; this symptom, which was only felt on walking, lasted altogether about an hour, after which it ceased entirely (third day), 2.

GENERAL SYMPTOMS

Objective.
Weakness (fifth day), 1.
Weakness, yet return of appetite (sixth day), 1.
Weak and debilitated (15 drops, after three hours and a half), 12.
Was obliged to go to bed, but could not undress herself, 6.
Restlessness (after nine hours), 3.
Restless and very nervous (40 drops), 12.
Subjective. [230.]
Malaise (40 drops), 12.
Malaise, with great weakness (third day), 1.
General malaise (after nine hours), 3.
At night, fatigue from lying in one position, 5.
General feeling of fatigue after waking, if the time had exceeded more than six hours, and a general weakness of body and mind, 4.
Neuralgic pains, soon followed by numbness over entire body and mind, 4.
Neuralgic pains, soon followed by numbness over entire body, with smarting and burning in nose (100 drops), 12.
On getting warm in bed, severe, sharp, flying pains in all parts of the systems; the pains in the limbs seemed to be in the cartilages of the joints, particularly the first joint of great toe, and streaking up the bones; in the abdomen, the pain was most in the region of the ascending colon, liver, and spleen; the pains of the head were all dull, except those of the occiput and those of the facial and optic nerves; the above pains kept him awake most of the night, those of the lower limbs being very severe, 5.
Principally manifested in provers of a voluptuous disposition, and of an excitable nervous temperament; more in females, 4.
( The chief characteristic of this remedy is a periodicity which is often clocklike in its regularity .)

SLEEP AND DREAMS

Sleepiness.
About 7 P.M., yawning and stretching, 2. [240.]
Sleepy and drowsy (65 drops), 12.
Sometimes very profound sleep, 4.
Sleeplessness.
Could not sleep (40 drops), 12.
Awake and restless all night, 6.
Restless night, without sleep, with a throng of confused ideas until 5 A.M. (prover had always slept well previously), 3.
All night, very restless, frequently waking, 5.
Restless sleep, 8.
During night, restless sleep, 7.
Restless sleep and confused dreams, in both sexes, 4.
Dreams.
Waking dreams, 6. [250.]
Frequently waking from dreams of pleasant social interviews with female acquaintances (second day), 5.
Dreamed (he seldom dreamed) all night of pleasant social interviews with female acquaintance, 5.
Dreamed of quarrelling with a dead sister and other dead friends; cried about it, and awoke with a nightmare, with sensation of a stone in the stomach, 6.

FEVER

Chilliness.
3 A.M., shivering all over with malaise and inclination to lie down; the shiverings are renewed by movement; coldness of the hands, feet, and nose; repeated transient flushes of heat in the face; and finally, towards 6 P.M., face constantly hot; lively expression, with smarting in the eyes, especially when closing them (second day), 1.
Slight chills only about 3 o'clock (eighth day), 1.
The chills continue all the time during the congestion of the head, and the hands, feet, and nose remain cold (second day), 1.
Towards 6 P.M., chilliness, quickly followed by severe frontal headache, extending into both parietal regions, with red eyes, itching of the eyelids internally and externally, icy coldness of the hands and of the tip of the nose , even at the height of the febrile reaction, while the rest of the face was red and burning-hot (after nine hours); a precisely similar attack at 5.30 P.M. (second day), 3.
Slight chilliness about 9 P.M. (twenty-first day), 2.
General coldness all the evening, 2.
About 6 P.M., (immediately after dinner), general coldness, shiverings in the back, ice-cold feet, burning hands, feeling in eyes as after much weeping, 2. [260.]
Forehead cold, and as if empty, in the morning, 4.
About 6.30 P.M., half an hour after dinner, chilliness in the back and legs, unusual paleness of the hands, red face, heaviness of the head, 2.
Feet very cold; went out barefooted in the snow, and went to bed, when they became warm (second day), 6.
Heat.
Heat over entire body (10 drops), 12.
Dry heat during the night, 2.
Warm feeling over surface of body (60 drops), 10.
Felt a flush or feverish glow spread over body (5 drops, after ten minutes), 10.
11 A.M., considerable fever; pulse 100 (second day), 5.
Flying heat in the face, alternated with chills towards evening, with bloated appearance, 4.
Feverish paroxysms every day (quotidian) in some provers, and every other day (tertian) in others, towards 8 o'clock P.M., preceded by depressed spirits, dulness of the senses, and pressive headache at noon; cramps, then contracting and tearing pains in the upper and lower extremities, with a cold sensation in the hands and feet; mouth dry; great thirst, and desire for cold water; chills and shivering; sometimes very strong shivering of the whole body; palpitation of the heart and hurried respiration; pulse weak and oppressed. These symptoms lasted from one to two hours, varied much in intensity; they were followed by a sensation of dry heat, and then of a profuse perspiration, full and quick pulse, with animated, red face, cold and pale in the apyrexia; thirst and desire for warm drinks, . [270.]

A certain state of mental excitement, and augmentation of vital energy, florid face, and a sensation of heat throughout the body; full and strong pulse; more or less perspiration, and no thirst. This group lasted from twenty to forty minutes in some, and disappeared after that time to return no more, without any further disturbance of health; whilst in others, the symptoms were prolonged from one to two hours, and were followed by- 2d.

Depressed spirits; dulness of the senses, and torpor of the mental faculties; general debility, languor, and faintings in some. When these symptoms are followed by those of the first group, the phenomena of both sets are often repeated, and at certain intervals of time; but neither of the two occur periodically, unless when they are together. Nor are they absolutely concomitant to pyrexia; for the paroxysms generally take place without them, as in the natural disease. It is for this reason that such phenomena were disconnected from category of the physical group; but whenever pyrexia occurs, or follows that condition, the symptoms, after weakness of the body and mind, are as follows: 3d.

Great thirst; yawning; cramps and painful feelings of contraction in the lower extremities; cold sensation in hands and feet; chills and shivering of the whole body; palpitation of the heart; pulse weak and oppressed; hurried respiration; chattering of the teeth and shaking of the whole body; scanty and highly colored urine; slight nausea in some, with yellow color of the skin and face in others; great debility; dilated pupils and confused sight. These symptoms lasted from one to two hours, and varied much in their intensity; after which- 4th.

Dry heat follows, with a full and quick pulse; animated face; profuse perspiration; longing for cold in some, and for warm drinks in others; and discharge of pale urine in large quantities. These symptoms lasted from two to three hours, and were generally followed by a desire to sleep. The provers felt as if they were contused; sound sleep in some, and somewhat agitated in others during the night.

The apyrexia generally lasted from fifteen to seventeen hours, after which, and in about the same time as the previous day , the paroxysms were repeated, as per Group 3d, and continued almost quotidian, 4.

CONDITIONS

Aggravation.
( Morning ), On rising from bed, dizzy, etc.; on waking pain in top of head; pressure in occiput; on rising from bed, could not see, etc.; on rising, tongue coated yellow; early, pricking of the tongue; on rising, gulping up of wind, etc.; flatulence, etc.; flatulent colic, etc.; at daybreak, genital excitement, etc.; on getting up, pain in back, etc.; at 3 o'clock, shivering, etc.; forehead cold, etc.
( Forenoon ), Pain in heel; at 11 o'clock, fever.
( Towards noon ), Buzzing of ears; pains in elbows, etc.
( Noon ), Pains in sacrum, etc.
( After noon ), About 5.30 o'clock, pricking of tongue, etc.; about 5 o'clock pricking itching of the tongue; 3 o'clock, pain in side, etc.; returned; 4 o'clock, pain in side, etc.; returned; towards 6 o'clock, chilliness, etc.; about 6 o'clock, immediately after dinner, general coldness, etc.; about 6.30 o'clock, half an hour after dinner, chilliness in back, etc.
( Towards evening ), Abdomen hard, etc.; chills in face, etc.
( Evening ), Head dull, etc.; pains in legs; about 7 o'clock, yawning, etc.; about 9 o'clock, slight chilliness; general chilliness; towards 8 o'clock, feverish paroxysm.
( Night ), Most mental symptoms; distensive headache; twitching of muscles of eyelids; hardness of hearing; saliva becomes sour; thirst; on getting warm in bed pain in region of ascending colon, etc.; at 10 o'clock, pains in joints; flying pains; on getting warm in bed, pains in all parts of the system; dry heat.
( Open air ), Headache.
( Cold ), After soreness of joints came on, flying pains.
( During dinner ), Colic.
( Motion ), After soreness of joints came on, flying pains.
( Rest ), Distension of stomach, etc.
( After talking ), Saliva becomes white, etc.
( After waking ), From more than six hours' sleep, feeling of fatigue, etc.
Amelioration.
( Towards noon ), Pressure at temple disappears.

Cedron