NATRUM ARSENICATUM.

12H2 O, a compound of Arsenic acid and Sodium. (The Arsenious acid becomes, during the process of preparation, converted into Arsenic acid.)

Preparation , Solution in distilled water in the proportion of 10 grains to 1 ounce (tincture), (Allegheny provings); Triturations (Gourbeyre's provings).

Authorities.

1 , Dr. Imbert Gourbeyre, l'Art. Méd., 17, 440 (1863), proving with the 6th trit., a dose three times a day for seven days, in a medical student. (Nos.

2 to 10 , provings of the Hom. Mat. Med. Club of Allegheny Co., Pa. Appendix to Hah'n Month. 1876.)

2 , J. H. Buffum, M.D., took 30th dec. dil., first to eleventh days, then the 3d dec. dil., eleventh to --- days; 3 , M. J. Chapman, M.D., took 30th, first to eighth days, then the 12th dil., eighth to --- days; 4 , J. S. Crawford, M.D., took 30th dec. dil.; 5 , J. C. King, M.D., took 30th, first to fifth days, 15th dil. fifth to twenty-first days, then the tinct., twenty-first to --- days; 6 , W. J. Martin, took 30th dec. dil. first to eleventh days, then 15th dil., afterward the 6th dil. (forty-ninth to fifty-first days); 7 , J. T. Miller, took 30th dil., third to seventh days, then 15th dil., twenty-fourth to --- days; 8 , R. Ramage, M.D., took tinct., repeated doses; 8 a , same, second proving; 9 , O. R. shannon, took repeated doses of tincture; 9 a , same, repeated proving; 10 , J. G. Thompson, took repeated doses of tincture; 10 a , same, second proving.

MIND

• Emotional.
• Feel depressed or blue (twenty-fifth day), 5.
• Feel gloomy, and want to sit quiet (seventh day), 10.
• Feeling as if something was impending, which caused him to move about (ninth day), 2.
• Disposed to be irritable (sixteenth day); irritable (nineteenth day); petulant disposition, and feeling of taciturnity gone (twenty-fourth day), 9a.
• Intellectual.
• Feel well; can study easily (third day); disposed to be reconciled to circumstances, favorable or unfavorable; feel like working hard; no undertaking too large for me (twelfth day), 3.
• Mind dull; cannot think clearly (fifth day), 8.
• Dull at 8 A.M.; stupid feeling, lasting through the day (second day), 3.
• Felt dull and stupid (thirteenth day), 9a.
• After recommencing the taking of the drug, feel dull and stupid (fifth and seventh days), 9. [10.]
• Dull, stupid, and forgetful, 9.
• Dull and indisposed to study; cannot be interested (fourth day); still unable to bring himself to study (nineteenth day); cannot concentrate mind readily (fifth, sixth, ninth, twelfth, and fourteenth days), 10a.
• Dull and languid all day (ninth day), 8.
• Stupid all day (fifth day), 10.
• No disposition to attend to his accustomed business (fifth day), 8.
• Requires an effort to attend to accustomed duties; feels dull; tries to write, but it requires an effort to form each word (second day), 10.
• Feel much better doing nothing; do not wish to think, to read, or to exercise; eight days have passed since I quit taking the medicine, but still feel its effects (fourteenth day), 9.
• Do not feel like thinking, or attending to any business (twenty-first day); not disposed to attend to business (twenty-second day); disinclined to read or accomplish any business (twenty-fifth day); unable to concentrate the mind on any subject requiring study; restless and unable to think (forty-second day); cannot think clearly and rapidly (forty-third day); more inclined to study, and apply myself to business; mind clear (fifty-third day), 5.
• Cannot concentrate mind on anything (eight day), .

HEAD

• Confusion.
• Confused feeling in head (sixth day), 10.
• Feeling of confusion through head (ninth and fourteenth days), 10a.
• Vacant feeling in whole head (eighth day), 8.
• General Head.
• Head feels dull (sixth and eighth days); head dull and heavy (eleventh day), 8.
• Head feels dull, as if he had taken cold (sixth day), 8.
• Dull, through other (confused) feeling in head (fourteenth day); head feels dull (sixteenth day), 9a. [30.]
• Head dull and heavy; clear, in afternoon (twelfth day), 6.
• Head feels dull and heavy, with aching pain in frontal region (third day), 10.
• Head feels dull (twenty-first day); head feels dull and heavy, with some aching on vertex (twenty-second day), 5.
• Slight dull feeling in head (fifth day), 4.
• Head feels heavy (fourth and seventh days), 10.
• Dull, heavy head all the evening, with slight nausea (fortieth day), 7.
• Dull, heavy feeling in head, lasting about three hours, at 6 P.M.; dull, heavy feeling in head, lasting five hours, after which the head ached violently, every motion of body aggravating it, even turning the head, and relieved by tying a handkerchief tightly around it, at 3 P.M.; dull, heavy feeling in head, especially in the vertex, increasing in severity till I went to bed, and was made worse by stooping or moving head; the aching took away the appetite, at 3 P.M. (sixteenth day), 4.
• Feeling of heat and fulness in whole head, at 8 P.M. (fourth day), 8.
• Feeling of fulness in the head all morning (eighteenth day), 5.
• Quite severe headache at intervals all morning (forty-seventh day), 5. [40.]
• Violent headache; every time he awoke the whole head ached (fifth day), 8.
• Heavy aching pain in ethmoid bone (fifth day), 10.
• Head feels sore (eighteenth day), 5.
• Throbbing in head on going upstairs (second day), 3.
• Wavering floating sensation on turning head quickly (twenty-seventh day), 7.

EYE

• Objective.
• Eyes red (eighth day); a little red, but not swollen (twenty-fourth day); a little red and watery (thirty-sixth day), 9.
• Eyes look swollen and bunged up (fiftieth day), 6.
• Eyes swollen (orbital region), (eleventh, twelfth, and fourteenth days); eyes swollen and conjunctiva congested; external part of left eye more congested than right; conjunctiva of right eye also congested (fifth day after recommencing taking); eyes swollen; left one much congested and red (sixth day after recommencing taking); eyes inflamed and swollen; left worse than right (seventh day after recommencing taking); eyes painfully affected, swollen, red, and watery; left worse than right (eleventh day), 9.
• Eyes swollen and painful (twenty-second day); worse immediately after rising (forty-third day); eyes swollen and congested (forty-fifth day); eyes slightly swollen and congested, at 9.35 A.M. (forty-sixth day), 5.
• Eyes somewhat swollen and agglutinated (thirty-eighth day), 7.
• Eyes and orbital region much swollen and agglutinated, on waking in the morning (fourth day); eyes much congested, and whole orbital region very much swollen (fifth and eighth days); eyes congested and swollen; not so much congested in evening (ninth day); eyes but slightly congested (tenth day), 8.
• Eyes puffy, at 8 A.M. (forty-first day), 7. [80.]
• Eyes more puffy and congested (fourteenth day), 9.
• Moderate congestion of vessels of white portion of eyes, but no disagreeable sensation in eyes (seventh day); eyes congested, especially in morning (tenth day); vessels of eyes congested, on waking in morning (eleventh day), 8a.
• Eyes much congested (third day); eyes congested (fourth day); eyes very much congested (sixth day), 10.
• Sclerotica slightly congested (fourth day), 9.
• A little whitish gum was seen in external canthus, in morning (twelfth and thirteenth days); eyes slightly gummed, in morning (twenty-fourth day), 8a.
• Subjective.
• Eyes feel tired and painful, especially in the sunlight (twenty-first day); eyes have felt tired all day, and painful when reading or writing (twenty-fifth day), 5.
• Eyes feel heavy (eighth day), 10a.
• Eyes felt heavy, in evening (after third dose, seventh day), 1.

EAR. [160.]

• Shooting pain over right ear, in afternoon (seventh day), 6, 7.
• Dull of hearing at all times, but more so to-day (fourth day), 10a.
• Annoyed by rushing noise in right ear, lasting from ten to fifteen minutes, and resembling the escaping of steam from an engine just starting, and synchronous with the pulsation of the temporal artery (have been troubled with it before, but not lately), at 9.40 P.M. (thirty-seventh day), 5.

NOSE

• Objective.
• Right side of nose and over bridge a little red; large pimple on side of nose not so sore, and a little indurated (fifth day), 10a.
• Both nostrils inflamed, and indurations in both (fiftieth day), 5.
• Nasal mucous membrane thickened, and the nasal passages somewhat obstructed (eleventh day), 8a.
• Thickening of nasal mucous membrane; can inhale air, but finds it difficult to exhale (eleventh day); nasal cavities feel as if stuffed, but air can be drawn freely through the nose (fifteenth day), 10a.
• Frequent paroxysms of sneezing through the day (fifth day), 2.
• Through the day considerable sneezing (twelfth day); sneezing (fourteenth day); sneezing brought on by an inspiration of cool air on moving about during morning, accompanied by a free watery or semi-mucous discharge; sneezing renewed every time he went into cool air, or took a fresh inspiration of cool air (fifteenth day), 10a.
• Watery discharge from nose (seventh day); catarrhal discharge from nose, less in afternoon (ninth day); thin watery discharge from nose (tenth day); some discharge from nose (twelfth day), 8. [170.]
• Free watery discharge from nostrils (twelfth day); all afternoon and evening (thirteenth day); rather copious watery or semi-mucous discharge all day (fourteenth day); discharge free till midnight, and since that time has been gradually diminishing (fifteenth day), 10a.
• Nose commenced discharging a clear watery substance after rising in morning; discharge from nose so profuse as to require the almost constant use of the handkerchief (sixth day); discharge from nose very profuse and watery (seventh day); discharge whitish, and becoming thick (eighth day); discharge from nose tough and yellowish (ninth day), 10.
• From left nostril a watery, non irritating discharge, in morning on rising, continuing till 10 A.M., becoming much less after that hour (fourteenth day); at times through the day, considerable discharge from nostrils, quite fluid from the left, and more gluey from the right nostril, with considerable chafing from frequent use of handkerchief (fifteenth day); nose discharging (sixteenth and seventeenth days); profuse discharge of a watery mucus from nose (eighteenth and twentieth days); both nostrils commenced discharging freely, at 9 A.M. (twenty-second day); all day a free discharge of yellowish mucus from both nasal cavities (twenty-third and twenty-fourth days); at times a watery mucous discharge from both nostrils, most free from the left thirty-sixth day), 9.
• Some indications of exudation from nasal mucous membrane setting in (eleventh day); slight discharge of mucus from both nasal cavities (twelfth day); moderate discharge of a tenacious whitish mucus from nasal cavities (thirteenth day); still a little watery discharge from nostrils (twenty-fourth day), .

FACE

• Objective.
• The complexion a little red or purplish (ninth day); natural (twenty-second day), 9a. [190.]
• Face flushed and hot (third day), 10.
• Face a little flushed (eighth day); took none of the drug for twenty days, and on the seventh day after recommencing it, face again flushed, 9.
• Entire face swollen, orbital region more than any other part, in morning on waking (twelfth day); bloating of face, seen while taking drug, gone (twenty-fourth day), 8a.
• Face feels puffed up and hot (fifth day), 10.
• Malar bones feel large, as if swollen (seventh day), 10.
• Corners of mouth indurated and painful, the right worst, at 11.30 A.M. (fifty-first day); corners of mouth still fissured, the right worst, at 9.30 P.M. (fifty-third day), 5.
• Muscles of mastication feel stiff, and motion of jaw is painful (seventh day), 10.

MOUTH

• Teeth.
• Teeth and gums tender (twenty-second day), 5.
• Tongue.
• Tongue rather furry, but of natural color (twenty-ninth day), 10a.
• Tongue slightly coated (third day), 7. [200.]
• Tongue coated whitish-yellow (twenty-second day), 5.
• Slightly yellowish coating on tongue (forty-sixth day), 5.
• Tongue coated with a thin yellowish-white fur (fourth and fifth days); nearly natural in color, and but slightly furred (eighth and tenth days); rather cleaner (twelfth and thirteenth days); rather whitish and downy, with slightly metallic taste after taking a drink of water (fourteenth day); slightly furred (fifteenth and sixteenth days); moderately heavy whitish coat uniformly spread over tongue on getting up in morning (eighteenth day), 10a.
• Tongue slightly coated grayish-white, in morning (second day); slightly coated white, with a rough feeling (thirty-ninth day); coated with a grayish-white mucus (fortieth day), 7.
• Whitish fur on tongue, most dense near the base, and on getting out of bed (eighteenth day), 9.
• Slight whitish coating on tongue (twelfth day); tongue coated yellowish-white (thirteenth day), 6.
• Light whitish fur on tongue (fourth day); tongue deep red, considerably corrugated, and somewhat furred (eighth day); tongue not so red, still somewhat and the papillæ standing up plainly on posterior part (ninth day); on waking, tongue moderately furred, but no very unpleasant taste in mouth (eleventh day); on waking, tongue somewhat furred back, and the papillæ on posterior part prominent and large, and the anterior part fissured (fourteenth day); tongue cracked, red, and uneven, and slightly furred (nineteenth day), 9a.
• Tongue clean (second day); thin whitish fur over middle of tongue from tip to base, leaving a small well-defined space on each side clear and of natural color (fourth day); tongue a little corrugated, and posterior part covered with a whitish-yellow coating, becoming lighter the nearer the tip (seventh day); slightly furred, supposed to be inflamed to some extent (case of tobacco), (eight day); thin whitish coating over most of surface, edges an tip free (thirteenth day), 8a.
• Tongue large, moist, and fissured (tenth day); flabby and fissured (twelfth day); large, soft, and deeply fissured (fourteenth day); furred, whitish, more on back part (forty-third day), 9.
• Small blister on right side near base of tongue (thirty-seventh day), . [210.]

THROAT

• Objective.
• Throat purple-red, rough, and pitted in places, and studded with little patches of points filled with mucus (twenty-first day), 9.
• Throat somewhat red, color deepest within fauces, less on soft palate, and entirely lost on the arch; the parts within the pharynx, so far as can be seen, are redder than natural, but not complained of as being sore on swallowing (eleventh day); throat purplish-red, and looks raw, but no soreness on swallowing (twelfth day); pharynx and pillars of fauces are red, and their structures thickened and angry looking, but not sore on swallowing (thirteenth day), 8a. [220.]
• A quantity of tough yellowish mucus occupying the posterior nares and upper of pharynx (twenty-third day), 9.
• Considerable yellowish, rather consistent mucus drawn by inspiration and hawking from posterior nares (eleventh and twelfth days); but little discharge anteriorly through nares, but the usual amount of hawking and clearing of throat and posterior nares during early part of day (thirteenth day); can draw air freely through nostrils, but there is a feeling in posterior nares as if obstructed, preventing easy and clear articulation (seventeenth day), 10a.
• Hawking up of a grayish, viscid, tenacious mucus, with rough feeling in throat (third day); roughness of throat; a tenacious white mucus causes considerable hawking to free the throat, in afternoon (twenty-sixth day), 7.
• Hawking this morning, as for some days past, but less this afternoon (fifteenth day); hawking continues; the mucus hawked up is tougher, a little more yellow, and the hawking a good deal oftener (seventeenth and eighteenth days); hawking very troublesome all day, but worst in morning (twentieth day); hawking and clearing of throat continues till 10 or 11 A.M.; a very tenacious whitish-yellow mucus is brought away by hawking (twenty-fifth day); hawking continues; it was formerly troublesome in morning, but is now troublesome all day (twenty-ninth day), 10a.
• Subjective.
• Disposition to hawk frequently and clear the throat of a tenacious starchy-looking mucus (twelfth and thirteenth days), 8a.
• Disposition to hawk and draw from the posterior nares and throat a thick semi-solid whitish mucus, continuing through the day, but most annoying on lying down to sleep (twelfth day); hawking a great deal (sixteenth day); hawking worse in open air (eighteenth day); frequent hawking and clearing of the throat (twenty-fourth day); disposition to hawk and clear the throat of the same tenacious mucus (thirty-sixth day), 9.
• Throat dry, and when dry, cough most troublesome (nineteenth day); throat dry, and a lot of stiff tenacious mucus lodged in upper part of pharynx, which, on trying to dislodge, caused gagging; during day throat dry, sore, and empty; deglutition painful (twenty-second day); dryness of throat only occasionally felt (thirty-sixth day), .

STOMACH

• Appetite.
• Appetite poor (twelfth day); could eat no breakfast; had some appetite for supper (fifteenth day); appetite good (seventh day after recommencing taking), 9.
• Appetite not good; could eat, but had no relish for the food (eleventh day); had an appetite for breakfast (twelfth day); no appetite for either breakfast or dinner, but ate some upper (fourteenth day); no appetite for breakfast, or dinner, but felt hungry for supper (fifteenth day); appetite good (twentieth, twenty-fourth, and twenty-sixth days), 9.
• Could eat but little breakfast (ninth day); since leaving off medicine, some days since, appetite not so good, with some tenderness in epigastric region (fourteenth day), 8.
• For several days, have had an aversion to an accustomed cigar, and after smoking the symptoms grew worse (twenty-sixth day), 5.
• Appetite good (twenty-sixth day); no appetite except for juicy food or fruits (fortieth day), 7.
• Appetite increased (seventh and eighth days); appetite not nearly so good as when taking the drug (twenty-fourth day), 8. [250.]
• Appetite greatly increased, and digestion good (twelfth day); no appetite for breakfast (thirteenth day); hungry, at 11 A.M. (forty-first day); no desire for food (forty-ninth day); entire loss of appetite. Have eaten nothing for sixteen hours. At noon had no appetite, but took some food and a cup of coffee, which seemed to relieve my head for a time. Had a desire for pickles at supper, which I rarely eat. It gave me a relish for bread and butter, of which I ate freely, and by 8 P.M. felt much better (fiftieth day), 6.
• Appetite decreasing (twenty-first day); poor appetite (twenty-second day); appetite very good (forty-first day); am losing appetite; have eaten but little for four days past. Have eaten less each day (forty-fifth day); somewhat hungry, but feel worse after eating (forty-sixth day); appetite has improved rapidly the past few days, with tendency to eat more than is proper (fifty-third day); during last few days, appetite has increased wonderfully. Eat too much almost every day, cannot help it. Still seem to digest all that is eaten (fifty-eighth day), 5.
• Not the usual relish for tobacco (forty-fifth day), 5.
• Thirst.
• Have been thirsty till 10 A.M., all the past week (seventeenth day); thirsty on getting out of bed (nineteenth day), 9.
• Thirsty all day. Wanted water often, but little at a time (forty-third day); very thirsty, but feel worse after drinking (forty-sixth day), .

ABDOMEN

• Hypochondria.
• Shooting pain from short ribs down across left hypochondriac region, in afternoon (thirty-ninth day), 7.
• Shooting pains over liver frequent, but not severe, in morning (thirty-eighth day), 7.
• Sharp shooting pain in left hypochondriac region just before stool (fortieth day), 7.
• Occasional stitches in spleen (third day), 3.
• Umbilical and Sides.
• Occasional pains through umbilical region, through the morning, with frequent passages of flatulence (third day); occasional pains through bowels, with discharges of flatulence (fourth day); occasional pains through abdomen (seventh day), 10.
• Some pain in umbilical region from distension with gas, at 9 P.M. (forty-second day), 5.
• Dull pain in umbilical region before the stools, 8. [290.]
• A dull pain in umbilical region, which disappeared after a free discharge of gas, in morning (forty-first day), 6.
• Borborygmus in left side of abdomen, between the cartilages of the ribs and the anterior part of the crest of the ilium, felt frequently and accompanied by sharp pain (ninth day), 10a.
• General Abdomen.
• Rumbling in bowels, as if diarrhœa would come on, in morning (second day), 7.
• Some rumbling and pain in abdomen (twenty-second day), 51.
• Uncomfortable feeling in abdomen (second day), 5.
• Feeling of distress, commencing in epigastrium, and in a few minutes extending through the entire abdomen. Pain not severe enough to prevent sleep, but felt on stirring about room (third day), 10.
• Pains in abdomen, with urging to stool (eighth day); pains through bowels (twelfth day); the pain in abdomen seems to be caused by gas, as much of it is passed at stool. Waked at 3 A.M., by sharp cutting pains in abdomen, relieved by passing off flatus (fourteenth day); slight pains in abdomen, made him sick (fifteenth day), slight pains in bowels (third day after commencing to take the drug again in large doses), 9.
• Slight pain through abdomen, passing off by escape of flatus (nineteenth day), 9a.
• Slight pain through bowels, with some urging to stool (third day), 9.

RECTUM AND ANUS

• Gnawing pain in lower part of rectum, as if worms were boring in it, at 11.45 A.M. (forty-fifth day), 5. [330.]
• Excoriated condition of the anus, very painful at stool (fifth day), 7.
• Slight burning in the region of the anus, with constant feeling of a necessity to go to stool without passing, the feeling lasting all the evening (ninth day), 2.
• Tearing pain at the anus on passing fæces (second day), 7.
• Dull dragging pain in perineum and lower part of scrotum (twenty-second day), 5.
• Desire to evacuate the bowels, with inability to do so by straining (twenty-second day), 5.

STOOL

• Frequent stools of a muco-purulent character, with much flatulence and tenesmus during the stool, 8.
• Three soft, dark-colored stools, followed by slight burning at the anus (third day); three thin, dark-colored stools. Burning at anus more marked than before. Passages preceded by pain, with relief after (eighth and ninth days), 9.
• Large stool, preceded by cutting pain in hypogastric region, at 1.30 A.M. In about ten minutes another stool, also preceded by cutting pain. Yellowish watery stool, at 8 A.M. (second day), 3.
• Stool natural but twice in the day, which is increased (thirty-sixth to fortieth days), 7.
• Loose motion from bowels, at 8 A.M. (ninth day), 9. [340.]
• Copious papescent stool, at 11 A.M. (fortieth day), 7.
• One light, painless stool, at 7.30 A.M. (fourth day), 9.
• One copious, brownish, painless, laxative stool, at 9 A.M., with a great deal of flatulence (thirteenth day), 8a.
• One stool, almost black (thirteenth day), 9.
• Stools lumpy (twelfth day), 9.
• Awakened by pain in abdomen, and soon after had a copious lumpy stool, which came on so suddenly as to hurry me out of bed. At 8, and also at 11 A.M., had loose lumpy stools, with some wind (fifth day), 4 . Pain and irresistible desire for stool, the discharge being large and soft; afterward, one small, thin, dark, and slimy stool (fourteenth day); stool dark, large, and lumpy. One hour afterward, felt weak and nervous, the hands trembled, then a scanty stool, with burning after it (fifteenth day); little or no pain in bowels, some flatulence, but discharges regular and natural (seventh day after recommencing taking), 9.
• Desire for stool, at 10 A.M., which is unusual with me, as I always evacuate the bowels before retiring for the night. The stool is of a laxative character, with some griping and burning at the anus, but without flatulence. Bowels relieved by the evacuation (seventh day); stools mushlike, and readily voided (fourteenth day); painless diarrhœic discharge from bowels, at 10.30 P.M. (fortieth day); diarrhœic stool, with considerable tenesmus; stool very thin, and expelled with force. Evacuation relieved a pain in bowels, at 10.30 A.M. (forty-ninth day); diarrhœic stool, with a great deal of flatus and slight tenesmus, at 4 P.M. (fiftieth day), 6.
• Two discharges from bowels; the first part of each natural, the latter part laxative and pungent. Had a disposition to go to stool at two other times, which passed away when flatus was allowed to escape from bowels (tenth day); bowels moved at 7.30 P.M., and again at 5 P.M. First part of morning stool consistent, but latter part quite soft. Evening stool thin and lumpy (eleventh day); large liquid stool, preceded by pain, and a little pungent, at 6 A.M. (twelfth day); bowels moved once, with slight pain through abdomen previous to discharge. Stool small, pasty, and light brown, with slight burning in bowels after stool. Had occasion frequently to go to stool, when the passing off of gas or urine relieved the sensation, and no stool came (fourteenth day); bowels moved at 8 A.M., stool pasty, dark, and small. Stool again at 10 A.M., of same character, but small also (fifteenth day); bowels moved once. Stool soft, pasty, and dark (sixteenth day); after breakfast bowels moved once. Stool of moderate size, yellowish, and sticky (seventeenth and nineteenth days); bowels moved at 9 A.M. Stool scant and yellowish (twenty-first day); bowels moved in morning.

URINARY ORGANS

• Kidneys and Bladder.
• Dull aching in kidneys (thirteenth day), 3.
• Dull aching in region of kidneys, with profuse flow of natural-colored urine, and of natural reaction (thirteenth day), 3.
• Sore feeling in region of bladder, relieved by urinating (twelfth day), 6.
• Urethra.
• Burning when urine begins to flow (thirty-ninth day), 6.
• Micturition.
• More disposed to urinate than was his habit (sixth day), 8.
• Quite an increased flow of urine through the day (thirteenth day), 8a.
• Have been urinating much more freely and copiously since taking the remedy (fortieth day), 5. [360.]
• Frequent copious discharges of clear, watery-looking urine, without any disagreeable feeling (fourth day); less urine passed, but, still more than a normal quantity, and still clear (fifth day); urine clear as water and in natural quantity (fifteenth day), 10a.
• Compelled to get up to urinate; the quantity in excess of what is usual, but of natural color (second day); roused from sleep with urgent desire to urinate (third day); urine passed in greater quantities, and with urgent desire (thirty-sixth day), 7.
• Got up at 6.30 A.M., and passed more than the ordinary quantity of urine, but was cool last night (thirteenth day), 6.
• Had to rise twice through the night to urinate, passing a large quantity of pale urine (eighth day), 4.
• Urinated but twice in the past twenty-four hours (twelfth day), 9.
• Urine.
• Urine of a little darker color than usual (twenty-sixth and thirty-sixth days), 7.
• Urine light-yellow, cloudy, and a precipitate seen after standing two hours; reaction acid; sp. gr. 1029. Heat precipitates a dense, white granular, which dissolves when mixed with or when nitric acid is used, leaving the urine clear and of a reddish-brown color. A few epithelial scales, a cast, some fat-globules, and some phosphates seen under microscope. Urine at 9.40 P.M., opaque, but of natural and strong odor, acid reaction, and sp. gr. 1030. No albumen, but large quantity of phosphates (second day); urine a dark straw color, of mild odor, reaction acid, sp. gr. 1030, phosphates in abundance, at 5.10 P.M. (fourth day); urine has an acid reaction, and sp. gr. 1029; deposits of phosphates on standing, at 7.50 P.M. (twenty-first day), .

SEXUAL ORGANS

• A dull cutting pain, lasting about five minutes at a time, and coming about once in each half hour, was felt along and about the length of Poupart's ligament, occurring on both sides at the same time. After the subsidence of each pain, a sickening sensation in left testicle, as if caused by a blow, and lasting about ten minutes. During the time this sensation lasted, the testicle was extremely sensitive to the touch, even of the clothing, but this sensitiveness passed away each time the pain subsided (had same symptoms on taking the drug the first time), (eighteenth day), 10a.
• Emission during sleep last night (tenth day), 6.

RESPIRATORY ORGANS

• Larynx and Bronchia.
• Dryness of larynx; it feels as if inflamed. Great difficulty in detaching the mucus, which is very small in quantity, and of a dark slate color (forty-ninth day), 6. [370.]
• Very sensible constriction and burning in lower part of larynx, more markedly felt on right side (one hour after ten drops, second day), 7.
• For two evenings, a roughness in larynx, causing a disposition to hem, with a spasmodic dry cough (eleventh day), 6.
• During morning, more or less constant feeling of irritation through bronchial region, accompanied by a slight dry cough (eleventh day), 10a.
• Voice.
• Voice a little husky (fourth, eleventh, and thirteenth days), 8a.
• Cough.
• Dry cough, with feeling of tightness and oppression in middle and upper third of chest (eighth, ninth, and tenth days), 8.
• Slight dry cough, with feeling of oppression upon chest (sixth day); dry cough (seventh day); cough looser, but no expectoration (eighth and ninth days), 10a.
• Coughed a little; deep inspirations are followed by a cough (fourth day); more or less continuous dry hacking cough, worse in heat of room; came on about 4 P.M. (eleventh day); dry hacking cough all day (twelfth day), 8a.
• Slight dry cough (eleventh and twelfth days); coughs moderately, but does not expectorate any; has coughed more, but has not expectorated (fifteenth day); short, dry, hacking cough (sixteenth day); cough still dry, and more severe than at any previous time (seventeenth and eighteenth days); cough a little loose for first time while up during part of the night, but has been a great deal more severe and paroxysmal, lasting longer at a time, and again tight during the day (twentieth day); some turns of same dry cough (twenty-fifth day); cough now only noticed after walking or making some exertion requiring an increase of the volume of respiration; the cough is dry (twenty-ninth day), 10a.
• Last night and to-day, a disposition to hack and cough, with a little irritation in throat (tenth day); hacking cough without expectoration, most persistent in the forenoon (eleventh day); dry cough, causing him to gag, continuing all day, but worse during forenoon (fourteenth day); same disposition to cough and gag, but not to same degree (fifteenth and sixteenth days); dry cough (seventeenth day); cough worse in forenoon (eighteenth day); cough dry, and feeling of dryness down the trachea and into the bronchia (nineteenth and twentieth days); commenced coughing on waking; cough worse in heat of room (twenty-second day); cough dry, but not so continuous (twenty-third day); cough a little loose, but otherwise about as for the past four weeks. Once or twice per day a little starchy looking substance is dislodged from a spot about under the fourth rib, a little to right of sternum, at which point there is a little soreness on pressure (thirty-sixth day), .

CHEST

• Feeling in chest as if smoke had been inhaled, causing a cough (eleventh day), 8.
• Pain for greater part of day through anterior part of upper lobe of left lung, but no soreness on pressing the walls of chest over seat of pain (fourth day), 8a.
• Feeling of fulness and oppression in chest (third day), 10. [390.]
• Feeling of fulness and oppression through entire chest, accompanied by a sense of soreness, worse on inspiration, and continuing through the balance of the day and evening, with a short dry cough, which seems to arise from some irritation behind the upper half of the sternum (fourteenth day), 10a.
• A constricted sensation about chest, and feels at times like taking a deep breath, but has no cough (twelfth day), 6.
• Feeling of oppression in the chest (fifteenth day), 10a.
• Feeling of oppression in centre of chest, in afternoon (ninth and tenth days), 8.
• Lungs feel oppressed, as if by a heavy weight (fourth day); heavy oppressed feeling in the chest, requiring an effort to draw a long, full breath (fifth day); feeling of oppression in chest, with slight dry cough (sixth day); feeling of oppression upon the chest (eighth and ninth days), 10.
• Feels no oppression of chest since urinary secretion became free (thirteenth day), 8a.
• Sharp shooting pain between sixth and seventh ribs, at about the junction of the ribs with the cartilages, lasting but a few seconds, recurring again after an interval of half an hour, at 9.30 P.M. (thirty-seventh day), 7.
• Pleuritic pain in right side, over liver, in afternoon (fifth day), 7.
• Some soreness of chest, in morning (second day), 7.
• Feeling of soreness and oppression through chest during motion or exertion. Taking a full inspiration increases the soreness (eighth, ninth, and tenth days); chest feels sorer (fifteenth day); entire chest feels sore on taking an inspiration of any depth whatever (seventeenth day); has felt sore through the entire chest all day (twentieth day); soreness of lungs, as for some days past (twenty-first, twenty-third, and twenty-fourth days), 10a. [400.]
• Pain over region of lower ribs; they feel sore on pressure (second day), 7.
• Region between sixth and seventh ribs sore to pressure, in morning (thirty-eighth day), 7.
• Tenderness on pressure in supraclavicular region, continuing all day (eleventh day), .

HEART AND PULSE

• On putting ear to chest, sounds of heart heard distinctly through nearly every part of chest (fifteenth day); sounds so loud and distinct as to prevent hearing clearly the respiratory sounds (seventeenth day); can himself feel beats of heart through chest distinctly (eighteenth day); beats of heart violent on making any unusual exertion or continuing a usual exertion for any considerable time (twenty-ninth day), 10a.
• Pulse 98 (second day), 10.
• Pulse 80 (second day); 86 (third day); 80 (thirty-sixth day); 80, at 3.30 P.M. (thirty-eighth day); 84 (thirty-ninth day); 96 (fortieth day), 7. [420.]
• Pulse 76 (tenth day); 80, and intermittent (not usual with him), (tenth day); pulse 88 (fourteenth day); pulse 90 (fifteenth day), 9.
• Pulse 90, 8.
• Pulse 72, and full (second day); 90, at 7.50 P.M. (twenty-first day); 84 (twenty-second day); 90 and full, at 2.30 P.M. (twenty-sixth day); 85, full and regular (forty-first day); 84, full and regular, at 9.30 A.M. (forty-third day); 86, at 9.35 A.M. (forty-sixth day), 5.
• Pulse 88 (fiftieth day), 6.
• Pulse 86, and a little variable in volume, but regular in beat (seventh day), 8a.
• Pulse 72 (usually 80 to 85), a little irregular, variable in volume (eighth day); 72, and quite irregular in its beats (ninth day), 74, and but slightly irregular (tenth day); 76, and rather slender, but regular (twelfth day); 56, full and regular, at 6.30 P.M. (fourteenth day); 75, regular and full (fifteenth day); 78, variable in volume, but regular in beat (seventeenth day); 86, slender and irregular (eighteenth day); 78, at times slender, and at times full, and readily caused to fluctuate by change of position or effort of body (twentieth day); 82, full and regular (twenty-fifth day); 72, and rather irregular in volume and beat (twenty-ninth day), 10a.
• Pulse 66 to 69, and irregular, with from five to seven interruptions per minute (has been a little intermittent before, but is more so than usual now); at noon (fourth day); 76, soft and rather regular (tenth day); 96, slender at times, and at times full and very irregular (twelfth day); 95 to 96 all day (fourteenth day); about 100, slender and intermittent during early part of day, 80, in afternoon (fifteenth day); 80, and irregular (sixteenth day); 75, and slightly irregular (seventeenth day); 76, and a little irregular (nineteenth day); 80, and irregular, both in volume and beat (twenty-second day); 96, slender and rather irregular (thirty-sixth day), 9a.

NECK AND BACK

• Neck.
• Neck feels stiff (forty-eighth day), 6.
• Left side of neck feels stiff and sore (sixth and seventh days), 9.
• Began to feel a soreness commencing at the lower cervical vertebra, and extending as far down as the joints of and under both scapulæ; the sensation was first felt on moving the arms and shoulders, on getting out of bed at night (nineteenth day), 10a.
• Back. [430.]
• Feel sore about back and abdomen (twelfth day), 6.
• A little soreness in back (twelfth day), 6.
• Dorsal.
• Pain between scapulæ quite severe, causing an inclination of shoulder forward for relief; it is felt at every inspiration, the deeper the inspiration the severer the pain, lasting form 8 till 9 A.M., and gradually passing around below the point of right scapula to a position on right side of chest below ninth and across tenth rib. The part named is very sore on taking a full breath (eleventh day), 10a.
• On taking more than the usual volume of air into lungs, a stitching pain is felt in space between scapulæ, which continues until 10 P.M. (nineteenth day), 10a.
• Lumbar.
• Pains in loins, extending all over back, especially felt between the shoulders, and even affecting the arms, in evening (sixth day); the same pains returned (half an hour after first dose); pains became so violent that I could not go out all the evening (after second dose, seventh day), 1.
• Dull pain in lumbar region (fiftieth day), 6.
• Pain in region of right kidney, worse on walking (third day), 7.
• Slight tenderness in renal region (twelfth day), 9.
• Sacral.
• Aching low down in back, across sacrum. This symptom has been more or less constant during proving (fourteenth day), 9.
• Feeling of weakness in sacral region (sixth day), 8. [440.]
• Soreness on walking or stooping, first felt on getting out of bed in morning; very severe on pressure on each side of sacrum on a line with acetabulum, and worst on left side. When walking for some time the pain was easier (twentieth day), 9a.

EXTREMITIES IN GENERAL

• Joints feel stiff (fiftieth day), 6.
• Aching in all the limbs (eleventh day), 9.
• Rheumatic pains in the limbs, especially the lower, running from hip to toes, and worse when at rest, and better when moving; these pains remain a few moments in muscles supplied by the sciatic nerve; pains most severe in flexor muscles of thighs and legs (twenty-second day), 5.
• The pains in the extremities wander about, showing a preference for the joints and for the left side, but not restricted to that side (forty-sixth day), 5.

SUPERIOR EXTREMITIES

• Neuralgic pains from axilla to small finger, along inner part of arm, forearm, and hand, at 9. A.M. (thirty-eighth day), 5.
• For the past five days a weary aching on raising the arm; an aching is felt through the whole left arm; the aching is worse from pressure and motion (thirty-sixth day), 7.
• Rheumatic aching in right arm, principally in shoulder and wrist (second day), 7.
• Shoulder.
• Shoulder-joint cracks when elevating or depressing the arm. The pain felt in shoulder passes down the course of the median nerve to the finger end (thirty-sixth day), 7.
• Forearm.
• The flexor muscles of the left forearm on holding anything in the hand with the arm flexed became stiff (thirty-sixth day), 7. [450.]
• Occasional little flying pains in the fingers, palms of the hands, and forearm (fifteenth day), 3.
• During morning had an aching pain in the flexor muscles of the left forearm near their insertion at the elbow, while riding (thirty-eighth day), 7.
• Pain from the tips of the fourth and fifth fingers to elbow of left arm (forty-sixth day), 5.
• Hands.
• Frequently recurring sharp stitches along the palmar surface of the fourth metacarpal bone, between the carpal and phalangeal bones, articulating with that bone. Same in both hands, but not in both hands at same time (eighteenth day), 10a.
• The metacarpo-phalangeal bone of the right index finger is sore on pressure, so much so as to make it painful to hold the pencil for any time; was never troubled in this way before taking the medicine (thirty-sixth day), 7.
• Fingers.
• Nervous twitching in middle and index fingers of left hand (forty-first day), 6.
• Pain in second phalangeal joints of fingers (twenty-second day), 5.
• Rheumatic pain in right forefinger (twenty-seventh day), 7.
• Sharp pains in right little finger, at 9.45 A.M. (ninth day), 5.

INFERIOR EXTREMITIES

• Lower extremities feel heavy (fourth day), 10. [460.]
• Pain in left iliac region, hip, and knee-joint, with an occasional twinge in right knee, 8.
• Lower limbs ache. Pain is in the flexor muscles (twenty-third day), 5.
• Hip.
• Pain in left hip-joint (forty-sixth day), 5 ; when walking (ninth day), 8.
• Pain in left hip-joint and inner aspect of thigh (tenth day), 8.
• Pain in left hip-joint and along thigh in course of crural nerve, feeling as if the part had been bruised; worse when commencing to move the part, but better from continuing to move it, 8.
• Thighs.
• A weary feeling from the crest of the ilium down the outer side of both thighs to the knees, as if he had been taking too much exercise. Began in afternoon (fifteenth day), 10a.
• Aching in thighs (twenty-first day), 5.
• An aching for a short time, about midday, in anterior and inner part of left thigh (twelfth day), 9.
• An aching commenced at 3 P.M., in the anterior part of the thigh, extending to the leg and ankle in front, beginning slightly and growing worse till a restless uneasy feeling was produced, which lasted till he retired for the night, at 9.30 P.M., but did not prevent sleep, and was gone in morning (sixteenth day), 10a.
• Dull aching pain across sacrum and down outer sides of thighs as far as the knees, the whole of the thighs partaking of the feeling (twelfth day); weary aching across sacrum and down the limbs, the same as yesterday, till 10 A.M. From that time was walking nearly all day, and felt better while walking, but on sitting down the same feeling returned (fifteenth day), 9. [470.]
• Sharp pain on moving, below trochanter on left side, reaching through to left spermatic cord, which feels a little sore to touch; the pain came on twice suddenly, lasted but a few moments, and disappeared, returning on crossing the thighs (fifteenth day); pain under trochanter felt occasionally through the day as a moderate aching (sixteenth day), 9.
• Rheumatic pains shooting from the acetabulum down to the knee, lasting but a few seconds, worse on moving about (third day), 7.
• Thigh sore (fiftieth day), 6.
• Pain and soreness on inner side of left thigh, from the inguinal region to the inner edge of the popliteal space; felt also in a slight degree in the other thigh (twentieth day), .

GENERAL SYMPTOMS

• Objective.
• Venous trunks full when seen on surface (twenty-second day), 9a.
• Appetite as good as usual, but he has lost 5 pounds in weight (usual weight, 138 pounds), (twenty-ninth day), 10.
• Easily fatigued when walking (ninth to fourteenth day), 8.
• Listless, languid, wants to sit still (fifth day), 8.
• Has less strength than when he ceased taking the medicine seven days since (twenty-ninth day), 10a.
• In such a state of weariness and malaise that I could not eat dinner, 1.
• Great restlessness; cannot sit still for any length of time without considerable force of will (ninth day), 2.
• Cannot remain long in one position; must move about (eighth day), 8.
• Subjective. [500.]
• More impressionable to cold than formerly (thirty-seventh day), 8a.
• Feels nervous (sixth day), 8.
• Feeling of nervousness all through the body (fourth day), 10.
• Very nervous (twenty-first day); quite nervous and uneasy (twenty-second day); exceedingly nervous; cannot sit still without exercising all my self-command (forty-fifth day); very nervous; cannot hold pen steadily (forty-seventh day); still quite nervous (forty-eighth day), 5.
• Desire to keep quiet (seventh day); feeling of lassitude, and want to lie down or to sit (twelfth day); feeling very miserable, on rising, at 8 A.M. (fiftieth day); feeling languid and worthless (fifty-first day), 6.
• Disposed to remain sitting (tenth day), 9a.
• Feel tired all over (fifth day), 8.
• Got up this morning feeling tired and bruised-like in body and limbs (fourteenth day), 9.
• Very languid feeling during the day (eleventh day), 2.
• Felt weary on waking (fifteenth day), 9a. [510.]
• Feel very weak at times (fiftieth day), 6.
• Feel very much exhausted (twenty-first day), 5.
• Feels nervous and much prostrated (eighth day), 8.
• Unpleasant feeling of general indisposition (twenty-first day); went into country, and while away felt much better; had no uncomfortable feeling (twenty-sixth day); have felt pretty well for several days (thirty-sixth day); have at times through the day felt better, and at times worse (forty-sixth day); more cheerful, and better in every respect (fifty-third day); feeling better and more cheerful than before I took the drug; this condition, however, is wearing off; it was more noticeable some days since (fifty-eighth day), .

SKIN

• Objective.
• Some reddish irregularly shaped spots over nose are becoming irritable and tender; this appearance of the nose had not passed away from the time the drug was previously taken, twenty-two days before (fourth day), 10a.
• A brownish scaly condition of the surface of the chest which has been there for the past ten years is disappearing, and a reddish color of the surface of the chest and neck remains, distinctly marking the boundaries of the old eruption or discoloration (eleventh day); the chloasma over the chest and lower part of the neck, and also over part of the abdomen and along and over the rectus abdominis muscle, has changed to a moderately bright-red color, and seems to be disappearing (twenty-fifth day), 10a.
• Yellowish blotches, resembling moth patches, appear on the cheeks and forehead remaining a day or two (eighth day), 3.
• An eruption of diffused irregular patches, with numerous papular elevations, without areola, with pointed apex, on the face and neck; most abundant between the zygoma and the ramus of the lower jaw; a goodly number, however, on the neck, and more on the right side than on the left (forty-third day), 5.
• Within the last three days has appeared on the skin covering the left superior maxilla a number of hard, very red pimples, not very painful (fifty-first day), 6. [520.]
• A bright-red rash, blotchy and irregular in shape, without any prominence, appeared about 10 A.M. over forehead, and in an hour spread over the rest of the face (seventh day), 10a.
• Fine red rash on face and neck, most on right side (third day), 8.
• Fine red rash on the face and neck, most of it on the right side (third to sixth day); the fine miliary rash still on the face and neck (eighth day), 7.
• On retaking the medicine after a lapse of twenty days, the rash brought out by the first taking of the medicine did not again appear, 8a.
• Face and neck covered with a fine miliary eruption, with here and there a pustule or large reddish pimple (twenty-third day), 5.
• A boil appears on the outer hamstring of the left leg (eleventh day), 2.
• Have a small boil on the right side of the chin, and one on the tuberosity of the ischium (fifty-eighth day), 5.
• Ulceration (such as has heretofore occurred from a cold) at right commissure of lips, continuing three or four days (seventh day), 6.
• Subjective.

SLEEP AND DREAMS

• Sleepiness.
• Yawns frequently (ninth day), 10a. [530.]
• Feels drowsy (eighteenth day), 5.
• Heavy and sleepy (tenth day), 9a.
• Can scarcely keep awake (second day), 3.
• Extremely sleepy (third day); drowsy and sleepy while at work in the afternoon (twenty-fourth day); did not sleep well; woke often through the night (twenty-fifth day); yawning, without sleepiness, in the afternoon (thirty-ninth day); slept unusually well for eleven hours, although I usually sleep but six and a half or seven hours (fortieth day), 7.
• Slept soundly (fourth day); restless and wakeful, followed in the morning by a general depression (eighth day); restless full of dreams, with frequent waking (ninth day), 8.
• Slept soundly, but was restless, and tossed about without being aware of it, and, on inquiry, find that it has been so since the drug commenced to produce symptoms; when roused up at any time since taking the drug, he wakes nervously, as if in affright, which is not usual with him (sixteenth day); slept soundly, more so than usual, but tossed about, and when attempts were made to rouse him, he rose up in bed excitedly and lay down again, without being conscious of it, in the morning, which was not usual with him; finds it difficult to get to sleep; has a feeling of nervousness all the time, which seems to annoy and prevent him from going to sleep (eighteenth day); a restless feeling prevented his going to sleep till after 1 A.M., although he went to bed at 9.30 P.M. (twenty-ninth day), 10a.
• Had to lie on the face to get to sleep, but slept well through the night (second day); slept moderately well through the night (third day); slept poorly; would start up and be wide awake and much frightened (sixth day); slept better last night (eighth day), 10.
• Sleeplessness.
• Took a bath and went to bed, but was restless, and could not sleep till after 3 A.M. (fiftieth day), 6.
• Retired about 11 P.M., but could not sleep till after midnight on account of a restless tossing about (ninth day); sleep disturbed (eleventh day), 2.
• Sleepless all night (seventh day), 1.
• Dreams. [540.]
• Have been very restless for three nights, frequently waking to find the covers pushed aside and myself in another position from that in which I went to sleep; I usually rest in one position all night, not waking through the night (twenty-third day); had many dreams and was restless last night, am not usually so (fortieth day); was restless last night and dreamed, contrary to my usual custom (forty-seventh day); slept little last night, was very restless, and woke frequently (forty-eighth day), .

FEVER

• Chilliness.
• Disposed to get near the fire and remain there (fourteenth day), 9a.
• Very chilly on retiring; was compelled to cover up, although wife was perspiring beside me (twenty-fifth day); chills on back that made me shudder, in afternoon (thirty-ninth day), 7.
• Through the night was at times chilly for a few moments, then hot; heat dry and burning, involving entire frame, and lasting three or four minutes the time of the chilliness; this condition lasted from 11 P.M. till 3 or 4 A.M., and was unaccompanied by either perspiration or thirst, 8a.
• Heat. [550.]
• Temperature 98 1/5° under the tongue (twenty-fifth day), 10a.
• Skin hot and dry, at 7.50 P.M. (twenty-first day); skin hot, but little perspiration; temperature 97 7/10° in axilla (twenty-second day), 5.
• Skin hot and dry, with feeling of lassitude (twelfth day); skin very hot and dry (forty-ninth day); skin hot and dry (fifty-first day), 6.
• Felt hot while in bed, and got up feeling tired, with skin hot and dry; feel warm, though the weather is cool (eleventh day), 6.
• Face feels hot, and looks flushed (seventh day), 10a.
• Face feels hot, with dull feeling in forehead (fourth day), 8.

CONDITIONS

• Aggravation.
• ( Morning ), On waking, swelling of orbital regions; burning of eyelids; eyelids feel swollen; lachrymation; congestion of conjunctiva; eyeballs seem large; on waking, obstruction of nose; swelling of face; hawking of mucus; on waking, dryness of fauces, etc.
• ( Forenoon ), Dry cough.
• ( Night ), Pain in inguinal region.
• ( Open air ), Eye-symptoms; hawking of mucus.
• ( Cold air ), Sneezing.
• ( Heat ), Boring in temples.
• ( Pressure ), Boring in temples.
• ( Stooping ), Pain in temples.
• ( ), Boring in temples.
• ( Walking ), Pain in region of kidney.
• Amelioration.
• ( Night ), Cough.
• ( Walking in open air ), Dullness of mind.
• ( Walking ), Pain across sacrum; pain in thighs.

SUPPLEMENT: NATRUM ARSENICATUM. Authorities. ( 5 a , and 8 b to 10 b , J. G. Thompson, Hahn. Month., vol. xiii, 1878, p. 599, observations, two years after the provings given in vol. vi of the Encyclopedia); 5 a , J. C. King, M.D.; 8 b , R. Ramage, M.D.; 9 b , O. R. Shannon, M.D.; 10 b , J. G. Thompson; 11 , Dr. Gouffia, Med. Circular, 1859, vol. xiv, p. 254, took from the beginning of November till the next June, a dose at intervals of two days, increasing gradually from 5 milligrams to 4 centigrams.

MIND

• Feeling of nervousness all through the body. Feeling of gloom; want to sit quiet. Confusion and want of power to concentrate the mind on any subject, 10b.
• Am more restless than was formerly my habit, so much so as to be noticed by others. Not so cheerful as before the proving. At times feel irritable, and then have not the usual desire to study, although the mind seems clear, and the memory as usual, 8b.
• No mental symptoms have been observed, in my case, for eighteen months or more, but I notice that prover R. R. ( 8b ), with whom I am associated, has never fully recovered from the nervous restlessness and loss of power of concentration, 5a.

HEAD

• Dull aching pain in the frontal region on awaking in the morning; during the day severe pain in frontal region. Every motion jars the brain. Aching across the brow, over the orbits, and in the balls of the eyes. Face feels hot, and looks flushed at times, 10b.

EYE. [560.]

• The action of the drug on the eyes was very marked at the time the proving was made, and the symptoms have since been so persistent that I fear the results are permanent. The eyes feel constantly weak, as if the lids must be kept closed to protect the ball. The conjunctiva seems dry and painful. When reading or writing, the eyes soon become tired and painful. A slight exposure to cold or wind produces congestion of the conjunctiva. After looking at an object a short time it becomes blurred and indistinct; the eyes are very sensitive to light. All the eye symptoms are worse in the morning, become gradually less severe, and disappear towards evening. The eyes do not suffer especially from artificial light, 5a.
• Eyes congested; eyes and orbital region much swollen. Agglutination of the lids on awaking in the morning. Eyes sensitive to the light. Eyes smart as from wood smoke. Œdema of the orbital region. Inability to open the eyes wide as usual. Disposition of the lids to close. Inner surface of lower lid distinctly granular in appearance. Severe pain in the orbits and orbital region. The whole orbital region much swollen, and the bloodvessels of the ball and lids much congested. Smarting and lachrymation on going into the open air. Sight weakened, 10b.
• My eyes became sound as usual about seven or eight months after I ceased taking the drug have remained strong and well since, 8b.

NOSE

• Dull aching at the root of the nose. Nose stopped up, right nostril most. Must keep the mouth open to breathe during the night. Discharge from the nose very profuse, commencing clear and watery, gradually becoming thicker, till finally it is tough and yellow. Thickening of the nasal mucous membrane; can inhale air, but have difficulty in exhaling. Yellow tough mucus drawn by inspiration, and hawking from the posterior nares. Sneezing brought on by inspiration of cold air, 10b.
• The nasal mucous membrane is dry, the mucus becomes tough, hard, and sometimes when disloged causes bleeding. From the posterior nares there is a dropping of mucus, which at times collects in a tough and very tenacious mass, causing considerable hemming and hawking to dislodge it, 9b.
• Since taking the drug have been troubled with nasal catarrh. The nose feels stopped all the time, but is worse at night and in the morning. During the day there is very little discharge from the nose, but a feeling as though the mucous membrane were swollen. In the morning the nose feels stopped up, and pieces of hardened bluish-colored mucus are blown from it, after which the mucous membrane feels sore and raw. I take cold much easier than I used to, 8b.

FACE

• Face flushed and hot; feels puffed. Heavy aching pain in ethmoid bone. Malar bones feel large, as if swollen. Muscles of mastication feel stiff, and motion of the jaw is painful, 10b.

THROAT

• Thirsty, dry, stiff feeling in the fauces and pharynx. Hawking of tough yellow or grayish mucus. Thickening of the uvula, tonsils, and pharynx; irregular on the surface, swollen purplish-red, and covered with an abundance of yellowish-gray mucus. Soft parts of the throat thickened. Difficulty in modulating the voice. (The thickening of the mucous membrane of the fauces and pharynx did not entirely disappear for more than six months after I stopped taking the drug, but there was no soreness felt at any time), 10b.
• The fauces feel dry on inspiration and on deglutition; the dryness is worse in the morning, and always after a cold, 9b.

STOMACH

• During the whole time the appetite was excessive, 11. [570.]
• The tenderness of the epigastrium noticed during the proving remains in a moderate degree. Have had frequent attacks of indigestion, lasting several days at each time. At such times the stomach feels sore, and anything warm or heating causes a sensation of burning, and can be sensibly felt immediately on entering the stomach. Previous to engaging in the proving I had not experienced any tenderness or pain in that region, 8b.
• Tenderness in the entire epigastric region, most marked immediately below the ensiform. Pain through the abdomen. Bowels relaxed. Frequent passage of flatus. Feeling of nausea. Vomiting of large quantities of sour water. The odor of food is pleasant, but on attempting to eat it produces vomiting of a very sour fluid, 10b.

ABDOMEN

• The abdominal symptoms have not been prominent for some time; however, the bowels have not been regular since the proving, they are alternately relaxed constipated; gas accumulates very rapidly, producing pain, which is only relieved by motion of the bowels or escape of flatus, 5a.

RESPIRATORY APPARATUS

• Ever since taking the drug the respiratory mucous membrane has been unusually sensitive to the influences of cold and irritating dust or vapor. Every day for two years I have hawked up more or less thick white mucus, while thick yellow mucus has been discharged from the posterior nares. These symptoms are aggravated by the inhalation of dust, smoke, etc. There is a tendency to the formation of dry crusts in the nose; when these are removed blood follows. There is a pretty constant compressive pain at the root of the nose. After a trifling exposure to cold my throat assumes the red puffy appearance noticed at the time of the proving; no pain accompanies this condition, 5a.

CHEST

• Feeling of fulness and oppression in the chest. Dry cough. Cough looser, but no expectoration. Sharp quick pain in the anterior part of the chest, below the seventh rib. Soreness and oppression in the chest; worse on taking a deep inspiration. Tenderness on pressure in the supra-clavicular region. Lungs feel full and clogged. Respiratory sound very indistinct, 10b.
• In the right side of the chest, beneath the cartilages of the fourth and fifth ribs, where irritation, pain, and soreness occurred when proving the medicine, there is an uneasiness, which on any physical exertion occasions a teasing sensation, producing a dry hacking cough and slight soreness, but never any acute pain. These symptoms are aggravated by deep inspirations, by dust, and a close atmosphere, 9b.

HEART AND PULSE

• Pulse irregular, variable in volume, and slower than usual. The sounds of the heart are heard through nearly every part of the chest. Can feel the beating of the heart through the chest distinctly, 10b.

BACK

• Severe pain between the scapulæ, causing an inclination of the shoulders forward for relief, felt at every inspiration, and gradually passing around below the point of the right scapula to a position on the right side of the chest, below the ninth and across the tenth rib; soreness commencing at the lower cervical vertebra, and extending as far down as the points of and under both scapulæ. On taking a deeper inspiration than usual, a stitching pain is felt in the space between the scapulæ, 10b.

EXTREMITIES

• The neuralgic pains in the extremities produced by the drug reappeared frequently during the first year. At times they were quite severe, and would remain for several days at a time. Recently they have not given me any trouble, 8b.

SUPERIOR EXTREMITIES

• Sharp stitches along the palmar surface of the fourth metacarpal bone, between the carpal and phalangeal bones, felt in both hands, but not in both at the same time. The lower extremities feel heavy. On commencing to move, pain and soreness in the right knee-joint. Dull pain on the inside of the popliteal space of the right leg, accompanied by a disagreeable feeling through the muscular part of the posterior portion of the leg, which passed off while walking. Cramp in plantar surface of right foot. Aching in the anterior part of the thigh, extending to the leg and ankle, beginning slightly, and growing worse, till a restless, uneasy feeling was produced, 10b.

INFERIOR EXTREMITIES. [580.]

• The neuralgic pains in the lower extremities have returned at intervals, apparently without any exciting causes; they appear chiefly in the left thigh, leg, and foot, and the nerves supplying the flexor muscles are alone affected, 5a.
• Dull cutting pain, lasting about five minutes at a time, and coming about every half hour, is felt along and about the length of Poupart's ligament, occurring on both sides at the same time. After the subsidence of the pain, a sickening sensation is felt in the left testicle, as if caused by a blow, and lasting about ten minutes. During the time this sensation lasted the testicle was extremely sensitive to the touch, even of the clothing, but this sensitiveness passed away each time the pain subsided. Urine light-colored, and increased in quantity, 10b.

GENERALITIES

• Embonpoint very apparent; its discontinuance was followed by considerable emaciation, 11.

SKIN

• The rash noticed during the proving has made its appearance on the face and neck at irregular intervals since, but has not remained long at any one time. A squamous eruption (not noticed either before or while proving the drug) has appeared on the chest along the sternum. The scales are quite thin, whitish, and when removed leave the skin slightly reddened. When the scales are allowed to remain the parts covered by them become itchy, especially so when warm from exercise, 8b.