ARGENTUM NITRICUM.
By Timothy F. Allen — The Encyclopedia of Pure Materia Medica
Silver nitrate, Ag.NO3.
Preparation , Solution of the crystals in distilled water, for lower dilutions.
Authorities.
1 , Hahnemann, R. A. M. L., 4, 340; 2 , "J.", 22 years old man, Œst. Zeitschrift, 2, 1; 3 , "H.", man, 23 years old, ibid.; 4 , "M.", man, 36 years old, ibid.; 5 , "P.", woman, 30 years old, ibid.; 6 , "N.", girl, 18 years old, ibid.; 7 , "E.", man, 20 years old, ibid.; 8 , "K. M.", boy, 7 years old, ibid.; 9 , Graves, ibid. (quoted from Hygea, 9, 135); 10 , Th. Hall, ibid. (Med. and Phys. Journ., 1800), given to a woman for convulsions; 11 , Moll, ibid. (Handbuch d. Pharmak.); 12 , Stuppe, ibid. (Inaug. Dissert.); 13 , Oesterlen, ibid. (Handbuch d. Hidmittellehre); 14 , (Bull. de Thérap.), ibid.; 15 , (Gazette d. Santé), ibid.; 16 , Étienne St. Marie, ibid.; 17 , (Med. Chir. Zeit.), ibid.; 18 , Moodie, ibid. (Med. and Phys. Journ.), general statement; 19 , Gesnerius (De Secretis remed.), ibid.; 20 , Westphal., ibid. (Miscell. Nat. Curios.); 21 , Blancard, ibid. (Die neue Scheidek.); 22 , Boyle, ibid.; 23 , Nasse, ibid.; 24 , Boerhaave, ibid.; 25 , Hildegardis, ibid.; 26 , Kinglake, ibid. (Lond. Med. and Phys. Journ.), given to a man for epilepsy; 27 , Schneider, ibid. (Hufelands, J.); 28 , Balardini, ibid.; 29 , Hoffmann, ibid.; 30 , Barn, ibid.; 31 , Michaelis, ibid.; 32 , Ebers, ibid.; 33 , Cappe, ibid.; 34 , Burdach, ibid.; 35 , Richter, ibid.; 36 , Wedemeyer, ibid.; 37 , Badley, ibid.; 38 , De Lens, ibid.; 39 , Fodéré, ibid.; 40 , Currie, ibid.; 41 , Tanchon, ibid.; 42 , Glauber, ibid.; 43 , Venat, ibid.; 44 , Gutceit, ibid.; 45 , Brown (Lond. Med. Gaz., 1834), ibid.; 46 , Hudson, ibid.; 47 , Smith (Lond. Med. Gaz., 1837), ibid.; 48 , Meyer, ibid.; 49 , Roget, ibid.; 50 , Kopp, ibid.; 51 , Frank, ibid.; 52 , Hering, Hom. v. Jahrschrift, 10, 343; [A correction, not a proving. -Hering.]
53 , Lembke, N. Z. f. H. K., 11, 130 (20 drops of a solution of 1 grain to 1 ounce of water); 54 , J. O. Muller, Z. f. Hom. Aezte. Œst., 1, 45 (10 drops of 6 dil.); 55 , Krahmer (Monograph), Review in A. H. Z., 29, 62, took small doses, and once 1/4 grain; 56 , Schachert, Dissertation d. Arg. nit. (Review, A. H. Z., 29, 74), took 1/8 grain; 57 , Gaz. Med., 1832 (Rust's Mag., 40, and A. H. Z, 5, 133); 58 , Gamberini, Med. Neuigkeiten (A. H. Z., Mon. Bl., 3, 29); 59 , Poumarede, Journ. d. Chim. Méd., 1839; 60 , Barbier, Trait. d. Mat. Méd.; 61 , Lombard, Gaz. Méd. d. Paris, 1832; 62 , Köchlin, Wirkung. d. Metall.; 63 , Debeney, Recueil d. Mem. d. Méd., 1843, injection of 12 grains in a healthy urethra; 64 , Dawosky, Journ. d. Méd., etc., 1856; 65 , Balardini, Omodei Annali d. Med., 1826; 66 , Scattergood, Brit. Med. J., 1871, fatal poisoning of a boy. [Notes: "J." took, three evenings, a little of 1st dec. trit. in some water; "K." took same, five doses; "P." took same; "M." took same, afterwards took in evening, 10 drops of 2d trit., three doses; "K.M." took 2d trit. twice; "M." afterward took 6th dil.; "N." took 30th dil.; "M." also took 30th, two doses, longer proving; "E." took 30th dil., two doses; "P." took 30th. dil.]
MIND
- Imbecile appearance; he looks at people with a foolish expression of countenance, even while conversing with them on some serious subject; he behaves shyly and sillily, and talks in a childish manner. On lying down for the purpose of relieving his head, visions and distorted faces hover before his imagination, although his eyes are closed, even in daylight (30th potency, second day), 7.
- Apathy, with great debility, and tremulous weakness (1st potency), 2.
- Hypochondriac and gloomy mood; drawing pain in the forehead; yellowish complexion; sweetish-bitter taste in the mouth; dry, viscid lips; feebleness and febrile sensation; debility and weariness of the lower limbs (in the forenoon, at 11 o'clock, for one hour), (30th potency, third day), 4.
- Hypochondriac taciturnity, accompanied with dulness of the head, and beating in the whole day (30th potency), 4.
- Anxiety, which makes him walk rapidly, 1.
- He feels very much affected bodily and mentally; he does not undertake anything lest he should not succeed (6th potency), 4.*
- Irritated and anxious mood, in the morning after rising, accompanied with great nervousness, feeling of weakness and tremulousness (6th potency), 4.
- Alternation of clear consciousness, lightness of sense, and indifference (6th potency), 4.
- Dulness of sense, absence of thought, inability to think; he is unable to find suitable words for his ideas; hence he falters in his speech (2d potency, second day), 4. [10.]
- Difficulty to collect his senses; he found it extremely difficult to conceive and idea, with heat and fulness in the head (2d potency, third day), 4.
- He feels dull, as if he would do nothing, 52.
- Stupid feeling in the head when writing (30th potency, first day), 4.
- Weakness of memory; he is unable to think connectedly, and falters in his speech (30th potency, second day), 4.
- Stupefaction, with suffering look (30th potency, second day), 5.
- Total loss of consciousness, 59.
- Coma, 14.
- Coma, difficult to describe, 59.
HEAD
- Confusion of the head (2d potency, first day), 4.
- The whole day his head feels confused, especially the occiput, the left region of the vertex, and the forehead (2d potency, second day), 4. [20.]
- On waking in the morning from a sleep full of dreams, his head aches and feels confused (2d potency, first day), 4.
- The head feels confused, accompanied with whizzing in the ears, and hard hearing (30th potency, sixth day), 6.
- Confusion of the head, with feeling of stupidity, over night; in the morning, when waking, it is changed to fulness in the forehead, with stinging, digging in the same, increasing after rising (1st potency, fifth day), 4.
- Dull and confused state of the head, with beating in the whole body, and hypochondriac taciturnity, after dinner (30th potency, second day), 4.
- The head feels confused after drinking coffee.
- Vertigo, 60.
- Vertigo in the morning (30th potency, fourth day), 7.
- Vertigo with headache, 9.
- In the morning she was attacked with vertigo, as if she were turning in a circle, inducing her to squat down; lest she should fall; accompanied with headache (30th potency, second day), 6.
- Vertigo, more before the eyes (1st potency, first day), 4. [30.]
- Vertigo, with complete though transient blindness, 10.
- Vertigo, and buzzing in the ears, and general debility of the limbs and trembling, 11.*
- Vertigo and staggering gait, 12.
- Attack of fleeting vertigo, as if intoxicated (1st potency, first day), 4.
- Giddiness, as if intoxicated, accompanied with lassitude and debility of the lower limbs (30th potency, first day), 4.*
- Vertigo, with nausea and confusion of the senses (30th potency, second day), 7.
- Giddiness in the head, as if he would faint, the body feeling tired, but not disagreeably so (30th potency, first day), 4.
- Giddy, dulness of sense, and as if he had lost all sensations; accompanied with drowsiness (30th potency, first day), 4.
ARGENTUM NITRICUM. EYES
- Holloweyedness (30th potency, fifth day), 4. [120.]
- Bleareyedness (2d potency, third day), 4.
- Wild rolling of the eyes, the pupils being dilated and insensible to light, 14.
- After violent itching the evening before, dryness and blearedness of the eyes, circumscribed congestion, bundles of red vessels spread here and there, ecchymoses into the conjunctiva bulbi, 54.
- Ophthalmia, abating in the cool and open air, intolerable in the warm room, [°].*
- Ophthalmia, with intense pains, 15.*
- Burning and dryness of the eyes, early in the morning when waking; he had great trouble in opening them (2d potency), 4.
- Aching pain deep in the eye, early in the morning (30th potency, second day), 4.
- Pressure in the eyes, as if too full; heat and pain in the ball of the eye when moving or touching it; mucous flocks impeding the sight, and obliging him to wipe the eyes, in the daytime; a scarlet redness, which had appeared in the morning in the inner canthus of the right eye, extended considerably in the evening, looked very much heightened, and spread as far as the cornea; the conjunctiva, bulbi, and palpebrarum looked inflamed and infiltrated; the eye was affected with a stinging-itching pain, as if occasioned by a grain of sand which had become lodged in the eye; *gray spots and bodies in the shape of serpents moved before vision ; he saw as through mist; even the light of the candle, which was not tinged white, was enveloped in mist; the aperture between the edges of the lids became narrower, and he had to wink frequently (with general debility and increased temperature of the skin, 2d potency), 4.
- Heaviness over the eyes, which open with difficulty; increased by stooping; decreased toward evening, 53.
- Tearing, extending from the forehead into the left eye and side of the face; lachrymation of the eye, which looks red and glistening (30th potency, third day), 5. [130.]
- Violent stitches in the inner angle of the right eye (after two hours), 53.
- Itching and biting of the left eye (2d potency, second day), 4.
- *Neuralgic pain in left infraorbital region (lasted, with more or less severity, all winter), 56.
- Infraorbital neuralgia (left side), at first only now and then, but it became constant during the following winter, .*
EARS
- She thought a board had been placed before the left ear (30th potency, sixth day), 6.
- Tearing behind right ear (after one hour and a half), 53.
- Frequent stitches deep in the left ear (first day), 53.
- Twinging pain in the ears (30th potency, fourth day), 4.
- Tearing and twinging in the right ear (2d potency), 4.
- Painful stoppage of the ears, with headache (30th potency, fourth day), 4.
- Whizzing, feeling of obstruction, and hard hearing in the left ear (30th potency, fifth day), 5.
- Whizzing before the ears, with dulness of the head (30th potency, sixth day), 6. [170.]
- Ringing in the ears and deafness (1st potency, fourth day), 4.
- Clear ringing in the ears, in the morning in bed (30th potency, third day), 4.
- Clear ringing in the ears, confusing the senses; she imagines it is at a distance (30th potency, first day), 5.
- Clear ringing before the ears, passing into momentary deafness, with dull roaring (1st potency, first day), 4.
NOSE
- Readily bleeding pimple near the septum of the nose (2d potency), 4.
- Scurfs in the nose excessively painful when becoming detached, and occasioning bleeding (30th potency, sixth day), 4.
- Ulcers in the nose becoming covered with yellow crusts, 4.
- Coryza ; sneezing after tingling in the nose and the posterior nares (30th potency, first day), 4.
- Much sneezing (several days), 8.
- Coryza, with constant chilliness, sickly look, lachrymation, sneezing, and such a violent stupefying headache that she had to lie down (30th potency, third day), 5.* [180.]
- Disagreeable stoppage of the upper part of the nose, for three days, 10.
- Discharge from the nose resembling white pus, with clots of blood, 10.*
- When sneezing he discharges a purulent mucus from the nose, mixed with little spots of blood (2d potency, fifth day), 8.
- Discharge from the nose like white pus mixed with lumps, 10 . [After the three days of S. 180 the pus is said to have been like brain substance.]
- 8 A.M., several drops of blood from the right nostril, without previous blowing of the nose, touch, or motion (fourth day), 53.
- Blows blood from the right nostril (30th potency, fifth day), 4.
- He blows blood and puriform mucus from the nose, 8.
- The nose is obstructed, 8.
- Unpleasant stoppage in the upper part of the nose for three days, 10.
- At night, the nose is stopped, with much itching (2d potency, fifth day), 4. [190.]
- In the room the nose is obstructed; in the open air a thin mucus flows from it (30th potency, fourth day), 4.
- Pain and swelling of the right nasal wing (3d potency, sixth day), 4, 8.
- Sore pain in the nose when compressing the wings, 4.
- The left nasal bones are painful, as if bruised (1st potency, first day), 4.
- Rigidity and clawing in the nasal cavity (1st potency, first day), 4.
FACE
- Sickly appearance (1st potency), 2.*
- Sunken, pale, bluish countenance (2d potency), 4.*
- Leaden-colored countenance, with nausea (30th potency, second day), 6.
- Appearance of old age; the skin in the face is more tightly drawn over the bones, hence the muscles are more distinctly delineated (2d potency, second day), 4.
- Convulsions of the facial muscles, the mouth being almost locked, 14.
- Pressure on the left side of the forehead, and drawing in the left cheek (first day), 53.
- Dull, drawing, tearing pains from the right temple to the upper jaw and to part of the teeth (30th potency), 4.
- In the left cheek, a wandering pain like a crawling (after six hours), 53.
- Drawing in the skin of both cheeks (immediately), 53. [210.]
- 4 P.M., burning stitching on the left zygoma, then on the right (first day), 53.
- The lips and soft parts of the mouth have a bluish appearance (1st potency), 5.
- On the margins of the lips and about the chin are purple-red spots, and the interior of the mouth is covered with a whitish-gray crust (Beont.), 52.
- The lips are dry and viscid, without thirst (6th potency), 4.
- Boring deep in both sides of the chin (third day), 53.
- Drawing above the chin, under the skin (first day), 53.
- Drawing in the lower jaw, 53.
- Pain, as if beaten to pieces, in the body of the left lower jaw (30th potency, fourth day), 4.
MOUTH
- Exfoliation of a molar tooth, in the right lower jaw, impeding mastication, and causing an ulcerative pain and a vacillating sensation (30th potency, third day), 7.
- The teeth become affected and spoiled; whereas he formerly never suffered with toothache, and had perfectly sound teeth, he now suffered constantly with some pain in the teeth ever since he commenced the proving, which was felt especially when chewing, when eating sour things, and when introducing cold things into his mouth; besides this there is a grumbling and digging perceived in the teeth, especially those of the lower jaw, on the left side, as if they would become carious, 4. [220.]
- Raging in the carious molar tooth of the left side (30th potency), 6.
- Drawing through all the teeth of the lower jaw (second day), 53.
- 9 P.M., drawing through the lower incisors (first day), 53.
- Drawing in the molars, 53.
- In the morning, when washing his mouth, the cold water causes a sudden tearing pain in his teeth (30th potency, second day), 4.
- The teeth are very sensitive to cold water (30th potency, second day), 4.
- *After a time tenderness of the gums with a disposition to bleed; they were, however, neither painful nor swollen, 18.
- The gums are inflamed and stand off from the teeth in the shape of white indentations, especially painful when touched, 8.
- Loose, readily bleeding gums , which, however, were neither painful nor swollen, 18.*
- White tongue (1st potency, second day), 8.* [230.]
- White, slimy tongue (1st potency), 2.
- Yellowish-gray tongue (30th potency, second day), 7.
- Red, painful tip of the tongue; the papillæ are erect and prominent (2d potency, second day), 4.*
- Tongue dark-bluish in spots (1/2 grain), 56.
- Tongue smutty-brown (1 grain), 56.
- The tongue is swollen and painful, as if ulcerated (1st potency, fifth day), 5.
Arg. nit .), (second day), 53.
- Feeling of warmth at the tip of the tongue and then in the œsophagus (1/4 grain), 55.
- Troublesome tension and prickling of the palate; a few days after this a swelling with a wart-shaped excrescence showed itself, impeding deglutition (30th potency, seventh, ninth day), 5. [250.]
- Ulcerated crusts on the mucous membrane of the mouth, especially that of the left cheek (1st potency, fifth day), 5.
- Fetor from the mouth , in the morning (2d potency, third day), 4.
- Parched condition of the lips, mouth, tongue, and fauces, night and morning (2d potency), 4.
- Slight astringent sensation in the region of the lips, in the buccal cavity and in the tongue (6th potency), 4.
- Watery mucus in the mouth and in the posterior nares, day and night (1st potency), 8.
- Accumulation of watery saliva in the mouth (1st potency), 8.
- Watery mucus in the mouth and posterior nares, day and night (1st potency), 8.
- Ptyalism (30th potency, fifth day), 4.
- Astringent taste in the mouth, with accumulation of watery saliva (6th potency), 4.
- Metallic taste (from caustic), 52. [260.]
- She has a taste as of ink in the mouth, 6.
- Inklike metallic taste, with styptic astringency of the mouth (1st potency, first day), 4.
- Metallico-styptic taste in the mouth, like ink, immediately (1st potency), 2.
- In the morning, after rising, he has a clayish taste in his mouth, the tip of the tongue being white, the root yellow, with viscid lips and no thirst (6th potency, second day), 4.
- Pappy, chalklike taste in the mouth, viscid lips, thin mucous coating on the reddish-white tongue (30th potency), 4.
- Pappy, bitter taste, with viscid mouth (30th potency, fourth day), 7.
- Bitter taste (1/4 grain), 55.
- Very bitter taste, and sensation of warmth on tip of tongue, and afterward in pharynx, 56.
- Bitter, astringent, stinging, coppery taste in the mouth, with nausea and inclination to vomit, immediately after taking the drug (1st potency), 5.
THROAT
- Accumulation of mucus in the posterior nares, obliging him to hawk, in the forenoon (2d potency), 4.*
- Frequent accumulation of a tenacious, thick mucus in the throat, obliging one to hawk, and causing slight hoarseness (1st potency, first day), 4.*
- *Thick, tenacious mucus in the throat obliges him to hawk all the time, the whole day (1st potency, first day), 4.
- Accumulation of mucus in the mouth and fauces; he has to hawk and spit all the time, in the morning (1st potency), 8.*
- Burning in throat very severe (1 grain), 56.*
- *Rawness and soreness in the throat, 52.
- Scraping sensation in the throat caused hawking and cough (1/2 grain), 55.* [280.]
- Scraping in the throat (2d potency), 4.*
- Roughness in the throat, occasioning a short hawking (6th potency), 4.
- Roughness and scraping of the throat, as if raw and sore (6th potency, first day), 4.
- Roughness and dryness of the throat, with ulcerative pain, at night (2d potency), 4.
- Dryness and strangulation in the throat, with shortness of breath, at night (30th potency, fifth day), 6.
- Pain in the right side of the throat, as of an ulcer drawing and tension upward and downward; sensation as if a splinter were lodged in the throat when swallowing, eructating, breathing, stretching, and moving the neck, sometimes and undulating jerking and pulsating was felt in the throat, continuing for several days (2d potency), 4.*
- Titillation in the throat, as if caused by a little feather, obliging one to hawk (6th potency), 4.
- Redness of the velum palati, posterior nares, and isthmus (6th potency), 4.*
- *Dark redness of the uvula and fauces (2d potency), .
STOMACH
- Strong appetite, 4, 6.
- Unusual appetite (6th potency), 4.
- In morning, violent, insatiable hunger (second day), 53.
- In the evening, uncommonly violent, insatiable hunger (first day), 53.
- Urging desire for acrid cheese, 5.
- Irresistible desire for sugar , in the evening, 4.*
- Appetite rather poor (fifth, sixth, and seventh days), 53. [310.]
- Diminished appetite (2d potency), 4.
- No appetite; many eructations (1st potency), 2.
- No appetite; food tastes to him like straw (1st potency), 2.
- Sleepy repletion (2d potency), 4.
- No appetite at breakfast (1st potency), 2.
- Loss of appetite, nausea, and vomiting, 57.
- Eructations insipid (1/2 grain), 55.
- *Violent belchings (1st potency), 8.
- Belching immediately (30th potency), 6.
- Much belching in the morning (30th potency, third day), 5. [320.]
- (Most of the gastric derangements are accompanied by belching).
- Continuous repulsive sensation in the stomach and pharynx, 11.
- Nausea, 13, 27.
- Nausea transient (1 grain), 55.
- Slight nausea, which disappears after eating (1/2 grain), 56.
- Nausea and gagging without real vomiting (1 grain), 56.
- Nausea arising from the stomach and the præcordia, with desire to vomit (30th potency, third day), 5.
- Slight nausea in the stomach, with chilliness and shuddering, and accompanied with a peculiar sensation of rigor in the lower limbs (1st potency, first day), 4.
- Nausea, resembling hunger (6th potency), 4.
- Nausea, with gurgling in the abdomen (1st potency, first day), 4. [330.]
ABDOMEN
- Abdomen swollen and distended (thirtieth), 52.*
- He wakes in the morning, from shifting of flatulence, rumbling, and a sensation in the intestines as if he had to go to stool (1st potency, first day), 2.
- Emission of flatulence immediately (2d potency), 8.
- Emission of much flatulence , after dinner (30th potency, first day), 4.
- Flatulence (30th potency, second day), 4.* [400.]
- Coldness in the abdomen, which is painfully irritated (30th potency, fourth day), 6.
- Uneasiness in the abdomen, several time a day (1st potency), 5.
- Peculiar uncomfortableness and emptiness in the abdomen, with nausea (6th potency), 4.
- Fulness, heaviness, and distension of the abdomen, with anxiety , impeding respiration, after supper (30th potency), 4.*
- Painful tension and pressure in the abdomen, as if sore and ulcerated (30th potency), 4.
- Troublesome colic, like cramp, after a slight catarrh (30th potency), 4.
- Colic previous to the diarrhœa, 4.
- Oppressive drawing pain in the whole abdomen, down to the groin, with tension, as in ascites (6th potency), 4.
- Sensation as of a ball ascending from the abdomen into the throat (30th potency, third day), 6.
- Extremely disagreeable drawing down the whole left side of the abdomen, when standing (1st potency, first day), 4. [410.]
- Stitches dart through the abdomen like electric sparks, especially during a sudden transition from rest to motion, on the left side (6th potency), 4.
- Pain in the abdomen, as if sore, accompanied with great hunger, abating after eating, but a trembling setting in in the place (1st potency, second day), 5.
- Pain in the hypochondria (1st potency), 8.
- Hard pressure in the left hypochondrium (30th potency, first day), 4.
- Stinging in the liver (2d potency, second day), 8.
STOOL AND ANUS
- Stitches in the rectum (third day), 53.
- Creeping and burning in the anus (1st potency), 8.
- A good deal of frequently repeated itching of the anus, inducing him to rub until he became sore (30th potency), 4.
- Discharge of a quantity of ascarides, 30.
- Discharge of tænia, 31. [430.]
- Discharge of several yards of tænia, 40.
- A good deal of urging during the diarrhœa, 4.
- Stool copious, fluid, followed by vomiting, 66.*
- Two or three stools daily, softer than usual, 53.
- Liquid stools, dark-colored, and quite frequent, 61.
- *Frequent stools, with slight pains in the hypogastrium, 65.
- Daily, two or three liquid stools, with much mucus, 53.
- Three diarrhœic stools at short intervals, the first being papescent and copious, the next scanty and of a watery mucus of dark color (1st potency, first night), 2.
- Six liquid, brown evacuations of a fetid smell (first and second nights), 2.*
- *A slight colic wakes him from his uneasy slumber, and he had sixteen evacuations of a greenish, very fetid mucus, accompanied with emission of a quantity of noisy flatulence, in one night (1st potency), 8. [440.]
- 6 A.M., awakened by sudden urging to stool; the discharge copious, half-liquid, and bright yellow , without pain or straining; soon after, the same urging again; besides this two stools daily (fifth, sixth, and seventh days), 53.
- Diarrhœa, 61.
- Diarrhœa (1 grain), 56.
- Diarrhœa, transient, 57.
- Shifting of flatulence in the abdomen, in the morning, followed by two diarrhœic stools (1st potency), 8.
- Two diarrhœic stools in the evening (1st potency), 8.
- *Four evacuations of green mucus, with retching, vomiting of mucus, (30th potency, fourth day), .
URINARY ORGANS
- Stricture of the urethra (from cauterizing), 45.
- Oozing of mucus from the urethra (1st potency), 8.
- In the night, quite an abundant secretion of thick, white mucus; in about ten hours discharge of thinner mucus; micturition is free and no longer painful; at noon the mucous membrane is dry, 67.
- The urinary apparatus was at first greatly irritated, 18 . (Not mentioned by this author. -Hughes)
- Inflammation and violent pains of the urethra, with increased gonorrhœa, priapism, dysuria, bloody urine fever, 43.
- Heat, itching, and titillation, in the morning, when urinating for the first time (2d potency, fifth day), 4. [470.]
- Burning during micturition , and sensation as if the anterior portion of the urethra were constricted (2d potency), 4.*
- Burning, micturition and feeling in the urethra as if swollen ; the last portion of the urine passed off with difficulty (2d potency, second day), 4.*
- Burning after micturition (2d potency), 4.*
- Slight burning in the whole course of the urethra increased gonorrhœa, burning during micturition, painful tension during erections, chordee, bleeding from the urethra, shootings in the same from behind forward, 44.
- The urethra feels swollen, hard, and knotty (2d potency, third day), 4.
- The urethra is painful , as if closed up by swelling, and ulcerated (2d potency), 4.
- Drawing through the end of the urethra (after one hour), 53.
- Sore feeling in the urethra, even after micturition (2d potency, third day), 4.
- After urinating, a burning drop ran along the urethra (2d potency, second day), 4.
- Sensation as if something fluid were running along the urethra from behind forward (2d potency), 4. [480.]
- When emitting the last drop of urine, a cutting from the posterior portion of the urethra as far as the anus (2d potency), 4.
- Dragging pains during micturition (2d potency, third day), 4.
- Painful pushing in the urethra (3d potency), 4.
SEXUAL ORGANS
- Male.
- Chancre-like ulcers on the prepuce; at first their tips were covered with pus, but afterwards the ulcers became diffused through a pretty spacious depression, exhibiting the tallow-like coating of chancres (1st potency, on the ninth day), 8.
- Sensitiveness near the orifice of the urethra, 52.*
- Painful coition; the urethra felt as if put upon the stretch; absence of pleasure (6th potency), 4. [520.]
- In from twenty-five to thirty seconds, terrible pains, continuing at the same intensity for five minutes, then gradually diminishing and becoming very endurable at the end of an hour, extending even into and along the course of the spermatic cords, 63.
- The right testicle is enlarged and hard (2d potency, third day), 4.
- Want of sexual desire, the genital organs having shrivelled (30th potency, fourth day), 4.*
- Frequent nightly emissions, sometimes accompanied with lascivious dreams, 4.
- Three copious emissions in one night (1st potency), 3.
- Female.
- Hemorrhages from the uterus, 41.
- Hemorrhages from the uterus (a fortnight before the menses), only a few hours (1st potency, fourth day), 5.
- Excites the capillaries of the uterus, 46.
- Congestions to the uterus, 41.
- Pain during coition and violent bleeding afterward (from injection of a weak solution for a profuse leucorrhœa), 52. [530.]
- She had two orgasms at night, which she had never had before (30th potency, fourth day), 5.
- Suppression of the mucous leucorrhœa; it reappears in a few weeks, but less and milder, 5.
- Suppression of the menses, miscarriage, and metrorrhagia, 47.
- The menses appear at the usual period, but they are much more copious than usual, and are accompanied with cutting pains in the small of the back and groin, and contractive sensation in the latter (30th potency, sixth day), 6.
RESPIRATORY APPARATUS
- When lying down, after dinner, he perceives a whizzing and whistling in the larynx (in the throat and the bronchial tubes), occurring regularly as the pulse; the noise did not seem to be occasioned by accumulation of mucus, but by the movement of the blood; it was heard only when lying on the left ear (30th potency, second day), 4.
- Balls of soaplike mucus accumulate in the larynx, occasioning slight turns of cough, by means of which they are expelled (6th potency), 4.
- Internal soreness of the larynx and pit of the throat; worse in the morning, 52.*
- 2 P.M., much tickling in the larynx, without cough (second day), 53.
- Scratchy sensation in larynx provokes hawking and cough, 56.
- Irritation and titillation in the larynx, followed by accumulation of mucus in the larynx, occasioning a slight rattling and whizzing breathing, until the mucus is thrown off in small lumps (30th potency, fourth day), 7. [540.]
- Dry tickling in the larynx, occasioning a cough, in the daytime (1st potency), 8.
- 3 P.M., continued tickling in larynx, rather lessened on inspiration, followed by short, dry, shaking cough, almost wholly ceasing on sitting (first day), 53.
- Hoarseness, with roughness in the throat (2d potency), 4.
- Nightly hoarseness, with turns of dry cough, after which she throws off blood-tinged mucus mixed with saliva (30th potency, seventh day), 6.
- Suddenly, while lying quietly in bed, at night, sense of pressure in throat, and violent, short, dry cough, without tickling in larynx (second day), 53.
- Night-cough, occasioned by a titillation in the larynx (2d potency), 4.
- Cough, occasioned by a titillation in the throat (2d potency), 4.
- Violent titillation in the throat, obliging him to cough, before dinner, recurring at the same hour for several days (2d potency), 4.
- Dry, fatiguing cough, occasioned by a violent, almost burning, titillation in the throat, before retiring in the evening (2d potency), 4.
- Dry and hacking cough, several times a day (1st potency), 8. [550.]
- Occasional cough in bed, at night (30th potency, third day), 5.
- Paroxysms of dry cough at night, sometimes so violent as to induce vomiting (1st potency), .
CHEST. [560.]
- Accumulation of mucus in the chest (1st potency), 8.
- Nightly pain in the chest (2d potency, first day), 8.
- Burning in the chest, 18.
- Sensation of warmth between the scapulæ and the sternum, which, after awhile, changed to a pressure in the epigastric region (1/2 grain), 55.
- Warmth between shoulder-blades and sternum, afterward changing to a slight pressure in epigastric region, with frequent tasteless eructations, 56.
- A violent pain in the middle of the upper part of the chest, as if it would burst, after going upstairs; she must hold the chest with both hands, 52.
- Aching tensive pain in the chest, in various places of the chest, of the size of half a dollar (2d potency), 4.
- Sense of pressure on the chest, without palpitation of the heart, with need of deep inspiration, lasting half an hour; disappears on walking; returns in an hour, also when walking, but lasts only a short time (after six and a half hours), 53.
- Sighing, owing to oppression of the chest (30th potency, first day), 4.
- Fulness and anxiousness in the chest, with disposition to sigh (1st potency, first day), 4. [570.]
- Heaviness in the cavity of the chest, with desire to sigh, 11.
- Oppression of the chest, accompanied with a clawing sensation moving through the chest (6th potency), 4.
- Stitches in the chest (2d potency), 4.
- Stitches in the breasts (1st potency, fifth day), 5.
- The outer chest is painful to the touch (1st potency), 8.
- Itching of the chest and axillæ (30th potency, third day), 4.
- A violent pain in the left external breast (in the evening, when drawing on the boots), followed by a persistent severe sore pain in both pectoral muscles which are very sensitive if the arms are stretched to draw on to the chest; worse near the left nipple, 52.
- Sticking in the left side of the chest (1st potency, fifth day), 5.
- The mammary glands of the right side are painful, as if ulcerated, towards the axilla, especially when touching the part; when stretching the arm and turning the trunk speedily to one side, and oblong rounded protrusion is distinctly felt (30th potency, fifth day), 5.
HEART AND PULSE
- When walking, sensation of pressure in the region of the heart, without palpitation or cough; was not forced to stop walking, but only to breathe deeper; the feeling lasted some time after keeping quiet in the room (after seven hours), 53.
- Heart's action irregular, sometimes intermitting, with an unpleasant sensation in the chest, 55.*
- Action of heart irregular, sometimes intermits, with a plainly unpleasant sensation in chest; on attention to it, the irregularity is more severe; almost disappears on motion in open air, 56.*
- On walking, a sensation, several times, as if the heart were beating once or twice stronger, but without impediment from walking, and without oppression of breath, 53.
- Palpitation, 58.*
- Palpitation of the heart, and sensation of restlessness in it, several times (first day), 53.
- Sensitive palpitation, like a sudden falling from above toward the middle; goes away just as quickly, with pain in the middle of the upper part of chest, as if it would burst (30), 52. [590.]
- Palpitation of the heart , at night (1st potency), 2.
- Violent palpitation of the heart, accompanied with a faintish nausea, of which she had three paroxysms in one afternoon (1st potency, third day), 5.
- Throbbing of the heart, 11.
- Frequent palpitation of the heart on slight excitement, and also from rapid movement (first day), 53.
- Palpitation , caused by any sudden muscular exertion or emotional excitement, 55.*
- Toward evening, twice, palpitation of the heart on motion of the body (first day), 53.
- Palpitation caused by sudden violent exertion or mental excitement ; and in horizontal position, especially evenings, in bed, the unpleasant sensations in chest are worse, 56.
- The irregular action of the heart was worse when noticing it ; better when moving freely about, 55.
- Pulse 70; full and natural, 59.
NECK AND BACK
- Bounding pulsations of the left carotid at regular intervals, distinctly seen by the naked eye (30th potency, third day), 5. [600.]
- Clawing in the right anterior cervical muscle, resembling a cramp (6th potency), 4.
- Drawing, with pressure, in the top of the left shoulder, as of a load (6th potency), 4.
- Violent pressure between the shoulders, penetrating deeply, especially at the angle of the right shoulder, early in the morning, on waking (6th potency), 4.
- Tensive clawing pains in the back, 4.
- Nightly pains in the back, 4.
- Weight in the small of the back, which prevents him from sitting (1st potency, fourth day), 5.
- Violent pain in the small of the back, as if sprained, early in the morning, when sitting, the pain was so violent that he had to rise (1st potency, second day), 4.
- Pain in the small of the back, relieved when standing or walking (1st potency, fourth day), 5.
- Paralytic heaviness in the lumbar region, on the left side, extending into the hip-joint of the same side (6th potency), 4.
- The lumbar region feels rigid and as if put upon the stretch (6th potency), 4. [610.]
- The lumbar region feels bruised (1st potency), 8.
- The small of the back feels weary (1st potency, fourth day), 5.
- Violent pain in small of back (girl of 8), 54.
- Digging-up in the small of the back, not permitting her to bend (1st potency, fourth day), 5.
- Cutting in the small of the back and in the abdomen (1st potency), 8.
- Cutting in the small of the back and abdomen, even when touching the parts (1st potency), 3.
- Violent pain in the small of the back, as if sprained, in the morning, scarcely permitting him to rise, and not permitting him to walk about, except crooked; recurring in the same manner for four days in succession (1st potency, third day), 4.
- Pains in the kidneys, 41.
- Frequent complaints about pain in the small of the back and in the loins (1st potency, fourth day), 5.
- Heaviness and drawing in the loins, accompanied with great debility and weariness, trembling in the lower limbs, as after a fatiguing journey (1st potency, first day), . [620.]
EXTREMITIES IN GENERAL
- Chorea-like convulsive motion of the upper and lower extremities, 54.*
- *Lassitude and heaviness of all the limbs (third day), 53.
- *Paralysis of the extremities, 13.
- Sensation in all the limbs as if they would go to sleep or become rigid, 1.
- 5.30 A.M., in bed, violent boring in the left outer malleolus and in the left shoulder (fourth day), 53.
- After rising, internal drawing in centre of right upper arm, then in the flesh of the right thigh, below and internally (fourth day), 53. [630.]
- 10 P.M., while sitting, violent pressure in the soft part above the bend of the right knee, in the left little finger, and on the back of the left foot (first day), 53.
- Stitching in the bone of the right third finger, and on the dorsum of the foot (first day), 53.
UPPER EXTREMITIES
- Paralytic drawing pain in the whole of the upper right extremities (2d potency), 4.
- Drawing, pressing pain through the whole right arm, at times more violent on the back of the hand, or in the upper arm (after one and a half hours), 53.
- 6 P.M., while walking, violent pain in the muscles of the left side of the arm, toward the lower part of the thorax, into the muscles of the loins, increased by each inspiration, also by walking; lasts five minutes (first day), 53.
- 4 P.M., violent boring in the right shoulder (first day), 53.
- Pressing in the left shoulder-joint (after seven hours), 53.
- Violent pressure on the top of the left shoulder, while resting the arm, 53.
- Tension in the right axillary glands (1st potency), 8.
- Pain in the right axilla, as if strained or torn; upon raising the shoulder, the pain extended along the arm as far as the hand, where a prickling sensation was experienced (2d potency), 4. [640.]
- Tearing internally on the right elbow (second day), 53.
- Stitching about the right olecranon, rather violent and long-lasting; unaffected by motion of the elbow-joint, but somewhat aggravated while resting the joint, 53.
- Paralytic drawing in the bones of the forearm (6th potency), 4.
- Nightly bone pain of the ulna (30th potency, second day), 4.
- He wakes in the night owing to an acute pain in the left wrist-joint, as if sprained, accompanied with heat of the whole hand, and uneasiness in the hand, obliging him to change the position of the hand all the time; in the morning, a pimple is seen not far from the joint, the tip of which is filled with pus, and in which a stinging pain is experienced, as of a splinter which had been stuck in; the tip is raised upon a red, hard base of considerable extent (1st potency, first day), 4.
- Tension and stiffness in the left wrist on bending it, with a deepseated pain; disappeared toward evening (first day), 53.
- Violent pressure in the left wrist (after one hour), 53.
- Pressing in the left wrist (always at 10.30 P.M.), 53.
- Drawing in left hand (after one hour), 53.
- Spasmodic contraction of the adductors of the fingers; she can scarcely separate the closely compressed finger, 54. [650.]
LOWER EXTREMITIES
- Legs drawn up to abdomen by muscular contraction, 56.
- In the night his lower limbs, especially his knees, start up; the starting awoke him (1st potency), 8.*
- He vacillates when walking, feeling moreover extremely uncomfortable in the whole body, and unsteady in his limbs (30th potency, second day), 4.
- Staggering gait in the open air (30th potency, second day), 4. [660.]
- Weariness of the legs (30th potency, second day), 7.
- Paralytic heaviness and debility of the lower limbs, so that she did not know where to put them (1st potency, third day), 5.*
- *Lassitude and weariness of the lower limbs, accompanied with dizziness, as from intoxication (30th potency, first day), 4.
- Great debility and weariness in the lower limbs, the whole afternoon, as after a long journey on foot, accompanied with sick feeling, dread of labor, drowsiness, chilliness, and sickly appearance (1st potency, second day), 2.*
- When walking, compressive sensation in the whole left leg (after six hours), 53.
- Drawing through the whole right leg, on sitting (second day), 53.
- Sticking-drawing pain in the hip down to the tarsal joint (1st potency), 5.
- Paralytic weakness of the lower limbs, and emaciation of the same (2d potency, second day), 4.
- When walking, pressive pain below and in front of the left trochanter, which, on stepping, causes him to bend over; very frequent, but not at every step (first day), 53.
- Periodical nervous ("cramplike") drawing, from the hip down to the knees, in paroxysms, sometimes so violent that it caused her to exclaim; the drawing descended along the anterior surface of the thigh (ischias antica), (30th potency, third day), 5. [670.]
- Drawing in the left knee (first day), 53.
- Pressure in the right knee (after one hour), 53.
- Pressing in the right knee, when sitting and walking, and on the dorsum of the left foot (immediately), 53.
- Violent pressing in the right knee, also when walking, lasting a quarter of an hour; then, stitching pain deep in the tongue, lasting nearly an hour (second day), 53.
GENERALITIES
- Cachexia, emaciation, affection of the liver, dropsy, 50.
- Great emaciation, 58.
- Weight of body decreased, 56.
- Œdema of legs and ascites, 58.
- *Convulsions and twitchings, 66.
- Powerful excitation of the muscles and nerves, and consensual excitation of the nerves of the stomach, 33.
- Her nerves are so much affected, that she apprehends she will lose her senses, accompanied with constant chilliness (30th potency, third day), 5. [710.]
- Nightly nervousness (1st potency), 8.
- *Nightly nervousness, with heat and fulness in the head (30th potency, fourth day), 6.
- Convulsions, 33.
- Convulsive contraction of this or that portion of muscles, 13.
- Presentiment of the approaching epileptic fit, 1.
- Weakness, 58.
- Peculiar debility, 27.
- She feels so debilitated that she is scarcely able to walk across the room, complaining a good deal about rigidity in the calves (1st potency, third day), 5.*
- In the afternoon, he felt so weak, that he had to lie down, accompanied with an increase of warmth in the whole body, and heat in the palms of the hands (2d potency), 4.
- In the morning, after rising, he feels very much debilitated, tremulous, irritated, and apprehensive (6th potency), 4. [720.]
- *Tremulous weakness, accompanied with general debility , as after great physical exertions, and apathy (1st potency), 2.
- Great debility and despondency, 13.
- After breakfast, he feels extremely debilitated, nervous, tremulous afraid to undertake anything, lest he should not succeed (6th potency), 4.
- Nervous, faintish, tremulous sensation , as if a severe disease were going to attack him (30th potency, first day), 4.*
- Excessive debility, wretched appearance, and emaciation, 49.
ARGENTUM NITRICUM. SKIN
- Peculiar discoloration of the skin (argyria) from the blue-gray, violet, or bronze-colored tinges to the real black (after large and repeated doses), (numerous authors).
- Skin brown, tense, and hard, 58.
- Slight brown spots on upper part of chest, and on hands, 58.
- Brownish color of skin of lower extremities, 58.
- Repeated drawing in the skin of the left forehead and of the left cheek, as if a spider's web lay there (immediately), 53.
- Tumor-like, itching elevations on the scalp, etc. (2d potency, third day), 4. [750.]
- Scurfs in the nose (30th potency, sixth day), 4.
- Pimple near septum of nose (2d potency), 4.
- Ulcers in the nose, etc., 4.
- In the left corner of the mouth, a painful, inflamed pimple, forming, on the day following, a pock-shaped pustule, which, after a few days of efflorescence, passed into a hard pimple of a few day's duration (2d potency), 4.
- Pustule on the derma of the upper lip, arising from a painful, red, shining pimple (2d potency, second day), 4.
- Hard pimples in the vermilion border of the upper lip, paler than the lip, and sore to the touch (30th potency, third day), 7.
- Pimples on the chin and cheek, which rapidly fill with pus (6th potency), 4.
- On border of nape of neck, etc., irregularly shaped blotches, etc. (1st potency, sixth day), 4.
- Itching pimples on the back, the itching being especially felt in the evening, and obliging him to scratch (1st potency, fifth day), 4.
- Itch-like eruption, especially on the back (1st potency, sixth day), 4. [760.]
- The dorsum of the right hand and that of the index finger is covered with red blotches, which become transformed to yellow blisters upon a red base (2d potency, second day), 8.
- Itching blotch-shaped pimples make their appearance upon the lower limbs in the night (30th potency, second day), 4.
- Fatal dropsy, 51.
- Itching of various parts of the body, making him uneasy in the night (1st potency, sixth day), 4.
- A good deal of prickling itching in various parts of the skin, at night (2d potency, fifth day), .
SLEEP AND DREAMS
- Yawning and chilliness (6th potency), 4.
- Much yawning and drowsiness (at 5 o'clock in the evening), (30th potency, second day), 4.
- Long and deep yawning (at 10 o'clock in the forenoon, and in the afternoon), (6th potency), 4.
- Frequent inclination to fall asleep while sitting (third day), 53.
- Sleepiness when sitting; he had to exert himself to prevent himself from falling asleep (30th potency, first day), 4.
- She inclines to fall asleep in the evening, while sitting down (1st potency, third day), 5.
- Soporous condition, 13.
- Attack of sopor in the evening (30th potency, third day), 4. [780.]
- Sopor with tossing about, in the night; no sleep (1st potency), 2.
- Sleeplessness, with tossing about in the bed (1st potency), 8.
- Sleep very restless, she tossed about in the bed, and spoke aloud (2d potency), 8.
- Nights restless; in the morning all the limbs feel bruised, and the sides pain, 52.
- Had a restless night; was awake most of the time, or slumbered merely, and had dreams (30th potency, third day), 7.
- Restless night; tossing about, heavy dreams (30th potency, first day), 7.
- *Restless night; he woke almost every hour, and had an unrefreshing slumber, disturbed with dreams (30th potency, second day), 4.
- Restless night, with fantastic dreams (30th potency, first day), 8.
- Restless night, with headache and stupefaction (30th potency, third day), 5.
- Restless, stupefied sleep, with horrid dreams (2d potency), 4.* [790.]
- The night's rest is disturbed with a dull headache (2d potency), 4.
- In the morning he wakes from a slumber full of dreams, with dulness of the head (2d potency), 4.
- He wakes in the night with sore throat (2d potency), 4.
- He woke early in the morning, owing to shifting of flatulence, rumbling in the intestines, and sensation as if he would go to stool (1st potency), 2.
FEVER
- For four days, every evening, at 6 o'clock, attack of fever, 54.
- Feverish sick feeling, the whole afternoon; constant weakness and exhaustion (2d potency), 4.
- Febrile condition; during the whole of the forenoon she suffered with headache and chilliness, ate little at noon, and without any appetite; complained a good deal of nausea; in the afternoon, about 4 o'clock, she was seized with violent tumult and beating in the head, with heat of the head, creeping chills, the skin being dry and hot, accompanied with nausea, and inclination to vomit, and with great desire for something salt; she felt likewise so debilitated, that she was no longer able to remain out of bed; the desire for something acrid and sour having increased, she took, at 7 o'clock in the evening, some pot-cheese, which she devoured greedily; after this the symptoms improved, but the febrile sensation continued the whole night (30th potency, sixth day), 5.
- Shuddering over the whole body, which passed into a febrile chill, with goose-flesh and coldness, the head being hot and the hands cold, with nausea, the whole forenoon, recurring at the same period on other days (30th potency, second days), 8.
- General chill, followed after a short interval, by general heat; the former lasting longer, and returning quickly on uncovering, even during the heat, the latter with perceptible pulsation of the temporal artery; both stages without thirst, 54.
- Fever, after a meal; he feels chilly, goes to bed, feels extremely nervous and weak; the head feeling obtuse (2d potency), 4.
- Coldness all over, in the warm room, in the evening (1st potency), 2. [810.]
- Chilliness and headache, in forenoon (30th potency), 8.
- Chilliness and nausea after rising (30th potency, seventh day), 6.
- Constant chilliness, extends up the back and across both shoulders, worse after eating, and when he comes in from the open air, 52.
- The chilliness was accompanied with a pale, almost yellowish countenance, nausea, and empty risings (30th potency, third day), 8.
- Night-sweats, 4.
- Profuse night-sweat, 1.
- A good deal of night-sweat (30th potency, fifth day), 6.
- Sweat on the chest, at night (30th potency, first day), 6.
- Morning sweat (1st potency), ; (30th potency, seventh day), .
CONDITIONS
- Aggravation.
- ( Morning ), Vertigo; aching pain deep in the eye; mucus fills the eyes; rising in the ears; tongue dry; taste clayey; hunger excessive; belching; heat and itching on urinating; urging to urinate; internal soreness in the larynx; sweat.
- ( At. 6 A.M .), Sticking in left ball; sudden stool; tearing in head and fingers.
- ( At 8 A.M .), Violent boring in side of head and wrist.
- ( Morning, after rising ), Very debilitated.
- ( Morning, on waking ), Dullness of head; headache, and confused pressure between shoulders.
- ( Morning, when walking ), Burning and dryness of the eyes.
- ( Forenoon ), Urination more frequent.
- ( Noon ), Violent boring in left temple; suffocative cough.
- ( Afternoon ), Violent boring in right side of head; stitches and digging in the frontal eminence; palpitation; great debility and weariness in the lower limbs; weakness.
- ( At 6 P.M .), Fever daily.
- ( Evening ), Pain in right side of head; frontal headache; tongue dry; excessive hanger; desire for sugar; stitches in the spleen; diarrhœic stools; less urine; cough dry, fatiguing; itching pimples.
- ( At 10 P.M .), Sticking in the right ball.
- ( Night ), Smell of pus; sore throat wakes him; *colic and diarrhœa; *much urinating; cough; *cough and pressure in throat; hoarseness; pain in chest; palpitation; pain in back; acute pain in left wrist; cramps in calves; *nervousness; itching of skin, of border of neck, and scalp; sweat.
- ( Midnight ), *Scanty watery diarrhœa.
- ( Night, on waking ), Tearing in one side of head.
- ( Open air ), Headache.
- ( Bending wrist ), Tension and stiffness.
- ( After breakfast ), Very debilitated.
- ( Chewing ), Toothache.
SUPPLEMENT: ARGENTUM NITRICUM.
The following, taken from the original, is deemed worthy of insertion, in place of the fragmentary reference in volume i.
Das silber, Arzn. Betrachet. Dr. Krahmer, Halle, 1845, p. 84. Quoted experiments of Schachert, Diss. de usu Argenti nitrici intermo, Regimont, 1837.
He took 1/8 grain of Nitrate of silver in distilled water, frequently repeating the dose; slight burning in the stomach. Afterwards took 1/4 grain, then 1/2 grain, daily. The burning sensation in the stomach became quite severe. The tongue showed in various places a dark-bluish color, and in the stomach there was a sensation of increased warmth and some nausea; these symptoms disappeared after taking food. The stools and pulse were not affected. Some time after this, Schachert increased the doses to a grain, which he took an hour and a half after dinner. The burning in the throat was very severe. The tongue showed for several days a dirty-brown color. The warmth in the stomach increased to nausea and retching, without actual vomiting, and after a few hours gave place to a persistent, periodically aggravated sensation of compression in the stomach. Towards evening diarrhœa set in, and continued during the next day, with relief of the pressure in the stomach. The evacuations seemed thin, but their color was normal. In addition to these sometimes there was a distressing dull headache, seated especially in the forehead, and associated with a certain prostration and restlessness. Changes in respiration, pulse, and secretion of urine were not marked. On the third day all the symptoms of the drug action had disappeared. Eight days afterwards Schachert took 1 1/2 grain in the morning fasting. He experienced nausea and efforts to vomit. He felt unwell through the day and suffered from dull headache.
Krahmer's experiments on himself, p.
- When I began my experiment I was quite well and strong, but afterwards was sick, and my stomach suffered for many days after I had discontinued the use of the silver; I frequently had heartburn, from which I had never before suffered, though these symptoms gradually disappeared. But in their place there soon appeared an almost uninterrupted neuralgic pain in the left infra-orbital region, which for some moments became most terribly severe, and lasted with interruptions the whole following winter. At the same time the action of the heart became irregular, and the beats at times omitted, when I had a distinct disagreeable sensation in the chest. To this was added a constant sensation of faintness in the præcordial region. I found that on turning my attention to the action of the heart its irregularity became more marked, but on moving about freely the sensation at times entirely disappeared. Upon my disposition these symptoms had no effect. The paroxysms of anxiety at the heart were not associated with it. Physical movement was uninterrupted, only sudden violent muscular action, as for example, jumping or rapid running upstairs, or after emotional excitement, caused violent palpitation; the disagreeable sensations were least marked in a horizontal position, and in the evening in bed. Sleep was rarely disturbed by palpitation. Towards the end of the winter the attacks diminished in intensity. Physical signs of anything abnormal about the heart were entirely wanting, as I was assured by an eminent medical friend. The next summer all morbid symptoms had entirely disappeared. That these changes in my condition were really the results of the silver I have no manner of doubt; there is no other explanation of them, and I make this communication in hope that my colleagues, who may have the opportunity to make similar observations, may be able to verify them.
In observing the action of silver I have endeavored as far as possible to pay attention not only to all the subjective, but also to all the objective symptoms; changes in the pulse, temperature, and character of the urine have been especially observed. I lacked the proper apparatus to ascertain the amount of carbonic acid eliminated by respiration.
My average pulse in the morning after rising was 66; at noon, soon after returning from my visits, 72; and in the evening, ordinarly 68. A strict milk diet for more than two weeks had no effect upon the character of the pulse. My temperature is from 29.6° to 30°R. I examined the urine, keeping account of the total amount, specific gravity, amount of water, quantity of uric acid, urea, and incinerated salts.
In order to have correct data, I examined the urine from the 6th to the 19th of October. I rise at 6 A.M., breakfast on two cups of coffee, am busy reading or writing till 9, visit patients till 1, then take dinner; work till 5 in my office, make evening visits, take supper at 8, go to bed about 11. Noon and evening I usually drink a glass of beer or wine. From October 19th to November 6th, I kept a very strict regular diet; took daily 2293.7 grams of fresh milk, and 418. grams of white bread.
October 26th, I took 0.1 grain crystals four times; 27th same; 28th, 0.2 grain; 29th, the same; 30 th; 0.3 grain four times; 31st, 0.4 grain four times; November 1st, 0.5 grain four times; 2d, 0.6 grain four times; 3d, 0.8 grain four times; 4th, 1 grain four times; 5th, 6/5 grain four times.
A consequence of the strict diet was that the stools, which are usually regular, were affected, so that October 21st, one was evacuated only after violent and painful effort, and on the 23d there was no voluntary stool. After several hour's effort to evacuate hard fæces, I took 1 ounce of castor oil. In the evening there was a hard painful stool, and the next morning a pasty stool. On the 25 th, repeated the oil, and the night of the 25th and 26th, took in addition an extra 1/2 ounce of the oil. On the 28th again took oil, also on the 29th, and from the 29th to the 2d of November, I took daily a teaspoonful of castor oil, so that the stools continued without great difficulty. After November 3d, I did not require the oil, because the large amount of silver nitrate kept the fæces soft. November 2d, my stomach began to suffer. At noon, after taking milk and bread, I experienced a pressing sensation of fulness in the epigastric region. November 3d, especially towards evening, the whole abdomen was very tense. November 4th, there was violent headache, and I could scarcely force myself to take the necessary amount of nourishment. The night was restless; I could not remain in bed after 4 o'clock. November 5th, I was still more averse to food, though the taste was natural and the tongue not coated. Through the day I had violent headache. The following night was very restless. I rose at 3 o'clock, and took nothing but a glass of milk before noon. The headache was very violent. In the afternoon, after passing the last quantity of urine for examination, I took two cups of strong black coffee, after which I felt quite relieved. Supper was relished, but the next day I could take but a very small quantity of food on account of heart-burn. The action of the silver seemed to cause a sensation of satiety, and my stomach seemed to need less nourishment than in a state of health. In the morning I took 1/4 grain in a pill form with white sugar dry on the tongue. I immediately experienced a very bitter taste, followed by warmth in the tip of the tongue, then in the pharynx, after which these two symptoms seemed to alternate with each other. I drank a little distilled water, which was followed by slight eructations, and a sensation of catarrh in the fauces and larynx. At noon, before dinner, I dissolved my dose in a drachm of distilled water. I experienced a sweetish taste and feeling of warmth in the mouth. Three hours after dinner took 1/2 grain in distilled water. The sensations were the same as before, but perhaps more severe. The scraping sensation in the pharynx provoked hawking and coughing. After a quarter of an hour I had a sensation of warmth between the scapulæ and sternum, which gradually became a pinching and slight pressure in the epigastric region. This was followed by tasteless eructations. The next morning I took 1 grain in water, and had only a very bitter taste. After ten minutes there was only very transient nausea.
The relation of the urea to the solid constituents in my case is somewhat less than the average given by Simon in his
Handbook . I had an average of 26.3 per cent. of urea, perhaps dependent upon the peculiarity of my diet, which is generally vegetable. Under the effects of the milk diet this per cent. rose to 37.6, and the amount of uric acid became quite small, which during my ordinary diet was 0.6, but was now reduced to 0.045; the amount of solid constituents was not essentially changed by the silver, nor was the amount of urea perceptibly changed; the average was 33.5 per cent; the whole amount daily excreted was 1.5 gram. Uric acid entirely disappeared from the urine under the influence of the silver. The amount of incinerated salts during the milk diet remained very constant. After several days' use of the silver it rose slightly. In the evening of November 6th, there was found 0.127 gram of pure silicic acid; so far as I know no analysis of urine has shown a like amount of silicic acid. No changes were noticed in the circulation or temperature. Silver was not found in the urine.